The Biochemical Journal 1913 Vol 7

Excerpt from The Biochemical Journal, 1913, Vol. 7: Edited for the Biochemical Society The whole question of the course of the breakdown of the protein molecule within the tissues is one of the most obscure in physiology. We have now a fairly good idea of the form in which the protein is absorbed from the lumen of the intestine but its immediate fate is still unknown. Apparently however definite evidence is now collecting [Folin, 1912] in support of the view that no immediate synthesis, analogous to that of fat, takes place. Unquestionably, irrespective of the form in which the protein material is conveyed to the tissues, there is, soon after the ingestion of food, a fairly complete disintegration of the protein molecule as evidenced by the increase in the output of nitrogenous substances in the urine. Of course it might be maintained, as it has been, that this material arises not from the newly ingested material but from "effete" protoplasm broken down and discarded when a new supply of repair material is available. If this be so then the material excreted ought to bear some definite percentage relationship to the normal protein of the body, for example the ratio of sulphur to nitrogen in the urine should approximate to that of the average tissue as obtained say by the study of the sulphur and nitrogen ratio in complete starvation. It was thought that, by a careful study of the ratios of S: N after feeding with specially chosen foodstuffs, light might be thrown on: - (1) The rate of protein catabolism. (2) The nature of the material catabolised. Previous Work. Little work has been carried out in this field probably because of the fact that until recently the difficulty of carrying on a long series of sulphur analyses was considerable. Since the introduction of the very excellent and rapid method of S. R. Benedict this difficulty has largely disappeared. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

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Vols. 36- include Proceedings of the Biochemical Society.

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.