Terahertz Technologies For Biosensing And Biomedical Analysis

This book offers the readers an opportunity to acquire the concepts of artificial intelligence (AI) enabled sub-THz systems for novel applications in the biomedical field. The readers will also be inspired to contextualize these applications for solving real life problems such as non-invasive glucose monitoring systems, cancer detection and dental imaging. The introductory section of this book focuses on existing technologies for radio frequency and infrared sensing in biomedical applications, and their limited use in sensing applications, as well as the advantages of using THz technology in this context. This is followed by a detailed comparative analysis of THz electronics technology and other conventional electro optic THz setups highlighting the superior efficiency, affordability and portability of electronics-based THz systems. The book also discusses electronic sub-THz measurement systems for different biomedical applications. The chapters elucidate two major applications where sub-THz provides an edge over existing state of the art techniques used for non-invasive measurement of blood glucose levels and intraoperative assessment of tumor margins. There is a detailed articulation of an application of leveraging machine learning for measurement systems for non-invasive glucose concentration measurement. This helps the reader relate to the output in a more user-friendly format and understand the possible use cases in a more lucid manner. The book is intended to help the reader learn how to build tissue phantoms and characterize them at sub-THz frequencies in order to test the measurement systems. Towards the end of the book, a brief introduction to system automation for biomedical imaging is provided as well for quick analysis of the data. The book will empower the reader to understand and appreciate the immense possibilities of using electronic THz systems in the biomedical field, creating gateways for fueling further research in this area.​

Biosensing technology is rapidly flourishing in recent years due to the advancement of bio-MEMS/NEMS. However, the booming development of biosensors has not been very well addressed to the unmet clinical needs. Advances in Biosensing Technology for Medical Diagnosis initiates a headway into the realm of cutting-edge diagnostic tools which are expected to become routine clinical practice. This book aims to broaden the readers’ horizon and guide them in tailoring different biosensing techniques for specific diagnostic procedures. Key Features: - 12 chapters cover several aspects of biosensing technologies including working principles and clinical validations - highlights the state-of-the-art biosensing technology developed in all fields - provides information about specific applications of novel biosensors used in clinical diagnosis, - provides step-by-step guidance of microfabrication for biosensors - focuses on bridging the gap between the scientific and the clinical communities - provides information about the diagnostic applications of biosensors for different diseases (including infectious diseases and neurodegenerative diseases). - covers Information about unconventional nano/microfluidic biosensor systems - features contributions from renowned experts in the field of biomedical engineering Advances in Biosensing Technology for Medical Diagnosis serves as a reference for healthcare providers and biomedical engineers who are interesting in biosensing techniques in medicine. The information provided in this reference will also benefit healthcare policymakers who are interested in new technologies that can impact the delivery of diagnostic services in healthcare systems.

Terahertz Biomedical and Healthcare Technologies: Materials to Devices reviews emerging advances in terahertz biomedical and healthcare technologies, including advances in fundamental materials science research, device design and fabrication, applications, and challenges and opportunities for improved performance. In addition, the improvement of materials, optical elements, and measuring techniques are also explored. Other sections cover the design and development of wide bandgap semiconductors for terahertz device applications, including their physics, device modeling, characterization and fabrication concepts. Finally, the book touches on potential defense, medical imaging, internet of things, and the machine learning applications of terahertz technologies. Reviews the latest advances in the fundamental and applied research of terahertz technologies, covering key topics in materials science, biomedical engineering and healthcare informatics Includes applications of terahertz technologies in medical imaging, diagnosis and treatment Provides readers with an understanding of the machine learning, pattern recognition, and data analytics research utilized to enhance the effectiveness of terahertz technologies

Recent technological breakthrough in the field of Terahertz radiation has triggered new applications in biology and biomedicine. Particularly, biological applications are based on the specific spectroscopic fingerprints of biological matter in this spectral region. Historically with the discovery of new electromagnetic wave spectrum, we have always discovered new medical diagnostic imaging systems. The use of terahertz wave was not realized due to the absence of useful terahertz sources. Now after successful generation of THz waves, it is reported that a great potential for THz wave exists for its resonance with bio-molecules. There are many challenging issues such as development of THz passive and active instrumentations, understanding of THz-Bio interaction for THz spectroscopy, THz-Bio nonlinear phenomena and safety guideline, and THz imaging systems. Eventually the deeper understanding of THz-Bio interaction and novel THz systems enable us to develop powerful THz biomedical imaging systems which can contribute to biomedical industry. This is a truly interdisciplinary field and convergence technology where the communication between different disciplines is the most challenging issue for the success of the great works. One of the first steps to promote the communications in this convergence technology would be teaching the basics of these different fields to the researchers in a plain language with the help of Convergence of Terahertz Science in Biomedical Systems which is considered to be 3-4th year college students or beginning level of graduate students. Therefore, this type of book can be used by many people who want to enter or understand this field. Even more it can be used for teaching in universities or research institutions.

A number of applications including scientific spectroscopy, security screening, and medical imaging have benefitted from the development and utilization of new and emerging terahertz (THz) generation and detection techniques. Exploring recent discoveries and the advancements of biological behaviors through THz spectroscopy and imaging and the development of THz medical techniques, Terahertz Biomedical Science and Technology contains contributions from scientists and researchers in the terahertz biomedical field and is exclusively dedicated to new and emerging terahertz biomedical research and applications. This text offers an assessment of terahertz technology, and provides a compilation of fundamental biological studies conducted using terahertz waves. It introduces THz electromagnetic waves as a new tool for convergent studies, includes laser-based generation techniques and solid-state devices, contains a number of detectors, and discusses high-field generation methods. The material covers recent advancements in terahertz imaging for medical applications—most specifically in cancer diagnosis—reviewing the current status of the THz imaging technique for diagnosing cancers, and exploring the potential medical applications of THz radiation. It also considers the development of future medical applications using terahertz technology. Summarizes the recent progress made in THz waveguides, which are absolutely essential in the development of THz endoscopes Describes the dynamic imaging of drug absorption in skin, exploiting the sensitivity of THz waves to pharmaceutical materials Explores the principle and applications of THz molecular imaging techniques using nanoparticle probes Scientists and engineers involved in biological research and medical applications using optical techniques, as well as graduate students and instructors in optics, physics, electrical engineering, biology, chemistry, and medicine can benefit from this text which highlights new and emerging biomedical studies utilizing novel THz wave techniques.

With emerging biological threats from pathogenic microorganisms and increasing environmental pollutants, it is essential to ensure the safety needs of individuals and the ecosystem are met. Modern materials science and engineering has evolved over the years to better develop devices to test abnormalities. Affordability, accessibility, and reliability of any analytical system is the prime necessity for a modern diagnostic application. Health and Environmental Applications of Biosensing Technologies: Clinical and Allied Health Science Perspective presents a detailed overview on biosensor design systems and optimal fabrication technologies to create a greater impact on various industries and help organizations break existing performance tradeoffs to deploy biosensor technologies across inter/transdisciplinary businesses. The book presents novel and emerging trends in biosensor design and healthcare applications focused on API detection, communicable/non-communicable disease diagnosis, food quality monitoring, agro-environmental analysis, bio-defense, and industrial pollutant sensing. In addition, wearable biosensors, commercial products, and safety regulations for biosensing technologies are summarized. Provides a fundamental understanding on biosensor system design, biomarkers for communicable/non-communicable diseases, and bioreceptor immobilization techniques Integrates information covering biosensing technologies for clinical diagnosis, API detection, industrial/environmental monitoring, agro-livestock healthcare, and disease control Provides information on principles, advanced trends, and approaches for wearable biosensors Covers market trends with biosensing technologies/products and their commercial challenges

We have come to know that our ability to survive and grow as a nation to a very large degree depends upon our scientific progress. Moreover, it is not enough simply to keep abreast of the rest of the world in scientific matters. 1 We must maintain our leadership. President Harry Truman spoke those words in 1950, in the aftermath of World War II and in the midst of the Cold War. Indeed, the scientific and engineering leadership of the United States and its allies in the twentieth century played key roles in the successful outcomes of both World War II and the Cold War, sparing the world the twin horrors of fascism and totalitarian communism, and fueling the economic prosperity that followed. Today, as the United States and its allies once again find themselves at war, President Truman’s words ring as true as they did a half-century ago. The goal set out in the Truman Administration of maintaining leadership in science has remained the policy of the U.S. Government to this day: Dr. John Marburger, the Director of the Office of Science and Technology (OSTP) in the Executive Office of the President made remarks to that effect during his confirmation hearings in October 2 2001.

For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors. This includes both state-of the-art fundamentals and innovative applications of these techniques. The authors present a deep analysis of their particular subjects in a way to address the needs of novice researchers such as graduate students and post-doctoral scholars as well as of established researchers seeking new avenues. Researchers and practitioners who need a solid foundation or reference will find this work invaluable. This second of two volumes covers the incorporation of periodic structures in waveguides to exploit the Bragg phenomenon, optical fiber sensors, hollow waveguides and micro-resonators as well as a review of the tremendous expansion of terahertz technology for sensing applications.

This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.