Novel Advances And Approaches In Biomedical Materials Based On Calcium Phosphates

Research into the use of calcium phosphates in the development and clinical application of biomedical materials has been a significantly diverse activity conducted by a wide range of scientists, engineers, and medical practitioners, among others. The field of research in this area can, hence, be truly defined as interdisciplinary, and much interesting work leading to imaginative and innovative solutions for the improvement of health outcomes continues to be generated. It has been the intention of this Special Issue to summarise a number of current topical research advances in this area, as well as to review the important area of calcium phosphate-based biomaterials, namely, composites of hydroxyapatite with carbon-based materials. The scientific papers contained in this Special Issue report on advances in the areas of dental-based materials science, bone cements, use of biomaterials created from natural sources, influences of added agents such as adipose stem cells and statins on bioactivity as well as surface influences on electrical potential of biomaterials and uses of glow discharge methods to remove impurities from biomaterial surfaces.

Research into the use of calcium phosphates in the development and clinical application of biomedical materials has been a significantly diverse activity conducted by a wide range of scientists, engineers, and medical practitioners, among others. The field of research in this area can, hence, be truly defined as interdisciplinary, and much interesting work leading to imaginative and innovative solutions for the improvement of health outcomes continues to be generated. It has been the intention of this Special Issue to summarise a number of current topical research advances in this area, as well as to review the important area of calcium phosphate-based biomaterials, namely, composites of hydroxyapatite with carbon-based materials. The scientific papers contained in this Special Issue report on advances in the areas of dental-based materials science, bone cements, use of biomaterials created from natural sources, influences of added agents such as adipose stem cells and statins on bioactivity as well as surface influences on electrical potential of biomaterials and uses of glow discharge methods to remove impurities from biomaterial surfaces.

Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia

This book presents a state-of-the-art review of the latest advances in developing calcium- phosphate bone cements and their applications. It covers the synthesis methods, characterization approaches, material modification and novel binders, as well as the fabrication technologies of calcium-phosphate-based biomaterials in regenerative medicine and their clinical applications. It also highlights methodologies for fabricating scaffolds, biofunctional surfaces/interfaces and subsequently modulating the host response to implantable/injectable materials, and integrates a series of discussions and insights into calcium-phosphate cements and constructs in bone regenerative medicine. As such, the book not only covers the fundamentals but also opens new avenues for meeting future challenges in research and clinical applications.

Calcium phosphate materials are used in many medical and dental applications. Advanced Synthesis and Medical Applications of Calcium Phosphates covers the structure, chemistry, synthesis, and properties of both natural and synthetic calcium-based biomaterials and details a variety of medical applications. Depicts the latest advances in using calcium phosphates in bone regeneration and tissue engineering Includes the latest generation of regenerative biomaterials with an integrated perspective combining both research and clinical issues Provides an understanding of the clinical targets and requirements for regenerative medicine Detailing fundamentals through applications, this book helps biomaterials researchers to better understand the clinical targets and requirements for use of these materials for optimal synthesis and development.

Biomaterials serve as synthetic or natural materials used to replace parts of living systems or to function contact with living tissue. Biomaterials are intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body. A biomaterial is different from a biological material such as bone that is produced by a biological system. Artificial hips, vascular-stents, artificial pacemakers, and catheters are all made from different biomaterials and comprise different medical devices. This book presents new approaches to biomaterial development including multi-field bone remodelling, novel strategies for conferring antibacterial properties to bone cement, polyacrylonitrile-based biomaterials for enzyme immobilisation and functionalised magnetic nanoparticles for tissue engineering from around the globe.

Calcium Phosphates: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Calcium Phosphates in a concise format. The editors have built Calcium Phosphates: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Calcium Phosphates in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Calcium Phosphates: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

This book provides in-depth assessment on the latest clinical advances in multifunctional calcium phosphate nanocoatings and its influence on bone regeneration and early healing following implantation. A greater emphasis will be placed on the use of nanocomposite coatings to deliver biological materials such as mesenchymal stem cells, growth factors, bone morphogenetic and extracellular matrix proteins, and pharmaceutics such as simvastatin to improve and promote bone growth as well as reducing the timeframe needed for implant integration in both healthy and osteoporotic patients. The content of the book caters to clinical practitioners and researchers working in the field of biomaterials for bone regeneration.

The goal of this book is to provide readers with a broad appraisal of topics in global advancements in theoretical and experimental facts, and practical applications of nano-HAp materials based on their synthesis, properties, prospects, and potential biomedical treatments. The perspective of this book involves the preparation of crystalline nano-HAP materials including preferential orientation, various properties and new prospects in biomimetics, bone tissue infections, biomedical implants, regenerative medicinal treatments and a wide range of technological applications. This book is categorized into two main sections: Hydroxyapatite: synthesis, properties, perspectives, and prospects; and the application of hydroxyapatite: a synergistic outlook. Individual chapters provide a base for a wide range of readers from diversified fields, including students and researchers, who will find in this book simply explained basics as well as advanced techniques of specific subjects related to these phenomena. The book is made up of nine contributions, compiled by experts from wide-ranging fields involved in biomaterials/materials in science and technology from over 15 research institutes across the globe.

This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. The book then reviews general types of biomaterials – polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications – before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization – chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity – and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a broader selection of materials and implantable solutions. This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union.