Mortality Of Rheumatoid Arthritis In Japan

This comprehensive text expounds the pathophysiology, diagnosis, and treatment of lung disease associated with rheumatoid arthritis (RA), an autoimmune disease that primarily affects joints. Recent advances in therapy for RA provide the benefit of achieving a better outcome in patients with arthritis, and a large number of reports on RA are now available. Moreover, the American College of Rheumatology and the European League Against Rheumatism have proposed guidelines and recommendations for management of RA patients. Therefore, clinicians around the world can adequately understand how to manage patients who have joint symptoms in RA. At the same time, however, the management of RA patients who have lung problems has not been disseminated sufficiently, although lung disease is a common complication in approximately 30–40 % of patients with RA. Unfortunately, there has been a lack of tangible evidence regarding the pathophysiology, diagnosis, and management of lung disease associated with RA. Each expert author in this book elucidates the current status of knowledge about lung disease in RA and the management of RA patients with lung diseases. Thus this valuable collection benefits not only rheumatologists but also respirologists, radiologists, pathologists, general practitioners, and medical staff such as nurses who are involved in the management of RA.

This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA. During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments. Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.

The old saying we now know all about rheumatoid arthritis except what causes it and how to cure it may still be true, but we certainly have a number of clues. This book presents the cutting edge of developments in etiology, mechanisms of inflammation, disease manifestations and management of this common, crippling disease.

Rheumatism in Populations provides information pertinent to rheumatic diseases. This book covers certain systemic orders such as the systemic lupus erythematosus that frequently affect the joints. Organized into 16 chapters, this book begins with an overview of the history of the epidemiology of rheumatism. This text then examines the prevalence of rheumatoid arthritis in screened sample and in total population samples. Other chapters consider the relative significance of rheumatic disorders as a cause of loss of work as revealed by the National Health Insurance statistics. This book discusses as well the pathology of disc disorders, osteoarthritis, rheumatoid arthritis, benign polyarthritis, metabolic joint disease, general connective tissue diseases, and immune deficiency diseases. The final chapter deals with diagnostic criteria for population investigations of rheumatoid arthritis. This book is a valuable resource for rheumatologists, physicians, and medico-social workers. Readers who are interested in the study of rheumatic diseases will also find this book useful.

First Prize, Orthopaedics and Rheumatology, BMA Awards 2009 This state-of-the-art reference provides current insights into the etiology, diagnosis and management of rheumatoid arthritis. Leading international authorities in RA examine all of the latest scientific and clinical developments in understanding and managing this challenging disease, including new concepts in pathogenesis, epidemiology, risk factors, imaging, clinical outcomes and treatment. It’s the guidance you need to offer optimal care to your patients with rheumatoid arthritis. Presents the work of leading international experts in rheumatoid arthritis for guidance you can trust. Provides the very latest understanding of the pathogenesis of rheumatoid arthritis, including molecular pathways/mechanisms, and genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features of rheumatoid arthritis including articular, peri-articular and extra-articular manifestations, comorbidities, and outcome measures—disease activity, joint assessment, imaging, and more—for expert diagnosis and monitoring of disease progression. Examines evidence-based treatment options—including traditional and biologic DMARDs and combination therapies—as well as promising therapies on the horizon, placing up-to-date guidance on disease modifying or disease controlling agents at your fingertips.

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series