Mechanisms Of Dna Tumor Virus Transformation
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Author | : Leonard J. Rosenthal |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 171 |
Release | : 2001-01-01 |
Genre | : Medical |
ISBN | : 3805572476 |
Download Mechanisms of DNA Tumor Virus Transformation Book in PDF, Epub and Kindle
Approximately 15% of human cancer incidence can be attributed to virus infection, i.e. viruses represent the second most important risk factor (after tobacco consumption) for cancer development in humans. Today, five virus types are known to be involved in causing human cancer: papillomaviruses, retroviruses, herpesviruses, hepadnaviruses, and flaviviruses. This volume provides a comprehensive review of a number of DNA tumor viruses. Leading experts in the field of tumor virology discuss up-to-date information, focusing on the transforming genes of DNA tumor viruses, the mechanisms of transformation and the in vitro methodology used for their identification and characterization. In vitro studies have revealed several common mechanisms of viral transformation. Presented in a clear and concise manner, this book will be of value to students as well as researchers in the fields of general biology, molecular biology, cell biology and microbiology.
Author | : Blossom Damania |
Publisher | : Springer Science & Business Media |
Total Pages | : 805 |
Release | : 2008-12-19 |
Genre | : Medical |
ISBN | : 0387689451 |
Download DNA Tumor Viruses Book in PDF, Epub and Kindle
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Author | : Giuseppe Barbanti-Brodano |
Publisher | : Springer Science & Business Media |
Total Pages | : 440 |
Release | : 2013-11-21 |
Genre | : Medical |
ISBN | : 1489911006 |
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DNA tumor viruses have long been useful experimental models of carcinogenesis and have elucidated several important mechanisms of cell transformation. Re search in recent years has shown that human tumors have a multifactorial nature and that some DNA tumor viruses may playa key role in their etiology. The aim of this book is to assess our knowledge of DNA tumor viruses by reviewing animal models, mechanisms of transformation, association with human tumors, and possi bilities of prevention and control by vaccination. Animal models of tumor virology have contributed significantly to our under standing of the epidemiology and pathogenesis of virus-induced tumors. Bovine papillomaviruses induce papillomas in the intestine of cattle. The papillomas undergo a transition to carcinomas in cows feeding on bracken fern, which pro duces a toxin with radiomimetic and immunosuppressive functions. This example of cooperation between a virus and chemical carcinogens parallels the cooperative role of human papillomaviruses (HPVs) and herpes simplex virus type 2 (HSV-2) with environmental carcinogens in the pathogenesis of cervical cancer. Likewise, hepatocarcinomas appearing in woodchucks chronically infected by woodchuck hepatitis virus (WIN) provide strong support for the relationship between hepatitis B virus (HBV) infection and human hepatocellular carcinoma. Also, the fact that WIN DNA integrates closely to cellular oncogenes suggests a possible molecular mechanism for the tumorigenesis induced by HBV.
Author | : Giuseppe Barbanti-Brodano |
Publisher | : Springer |
Total Pages | : 464 |
Release | : 1995 |
Genre | : Medical |
ISBN | : |
Download DNA Tumor Viruses Book in PDF, Epub and Kindle
This single reference on DNA tumor viruses in animal models and humans presents the latest studies on mechanisms of virus transformation, their association with human tumors, and the possibility of prevention and control by vaccination. Chapters provide current information on the epidemiology and pathogenesis of virus-induced tumors and offer insights into future prospects of immunological intervention. Biomedical researchers, clinicians, and virologists will benefit from this key resource.
Author | : Sally Roberts |
Publisher | : Caister Academic Press Limited |
Total Pages | : 0 |
Release | : 2018-05 |
Genre | : Medical |
ISBN | : 9781910190791 |
Download DNA Tumour Viruses Book in PDF, Epub and Kindle
Topics covered range from an overview of the contribution of DNA tumour viruses to the cancer burden worldwide, and the molecular pathogenesis of virus driven cancers to vaccine development.
Author | : |
Publisher | : |
Total Pages | : 1254 |
Release | : 1984 |
Genre | : Oncogenic viruses |
ISBN | : |
Download RNA Tumor Viruses: Supplements and appendixes Book in PDF, Epub and Kindle
Author | : Robert C. Bast, Jr. |
Publisher | : John Wiley & Sons |
Total Pages | : 2004 |
Release | : 2017-03-10 |
Genre | : Medical |
ISBN | : 111900084X |
Download Holland-Frei Cancer Medicine Book in PDF, Epub and Kindle
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author | : Luis P. Villarreal |
Publisher | : Amer Society for Microbiology |
Total Pages | : 259 |
Release | : 1989-01 |
Genre | : Science |
ISBN | : 9781555810139 |
Download Common Mechanisms of Transformation by Small DNA Tumor Viruses Book in PDF, Epub and Kindle
Based on a 1989 conference in Newport Beach, California. Contributors, mostly from the US and France, present 17 papers that give overviews of common paths to transformation and present mechanisms of transformation and early gene function, the molecular basis for regulation of early gene expression,
Author | : Manfred Schwab |
Publisher | : Springer Science & Business Media |
Total Pages | : 1017 |
Release | : 2001-10-15 |
Genre | : Medical |
ISBN | : 3540665277 |
Download Encyclopedic Reference of Cancer Book in PDF, Epub and Kindle
This comprehensive encyclopedic reference provides rapid and focused information about topics of cancer research for the clinical and basic scientist, students and informed laymen. It will be readily accessible, both electronically and in print, such that it will be of value to both the scientific community and the public.
Author | : Wang-Shick Ryu |
Publisher | : Academic Press |
Total Pages | : 441 |
Release | : 2016-03-30 |
Genre | : Science |
ISBN | : 0128009993 |
Download Molecular Virology of Human Pathogenic Viruses Book in PDF, Epub and Kindle
Molecular Virology of Human Pathogenic Viruses presents robust coverage of the key principles of molecular virology while emphasizing virus family structure and providing key context points for topical advances in the field. The book is organized in a logical manner to aid in student discoverability and comprehension and is based on the author’s more than 20 years of teaching experience. Each chapter will describe the viral life cycle covering the order of classification, virion and genome structure, viral proteins, life cycle, and the effect on host and an emphasis on virus-host interaction is conveyed throughout the text. Molecular Virology of Human Pathogenic Viruses provides essential information for students and professionals in virology, molecular biology, microbiology, infectious disease, and immunology and contains outstanding features such as study questions and recommended journal articles with perspectives at the end of each chapter to assist students with scientific inquiries and in reading primary literature. Presents viruses within their family structure Contains recommended journal articles with perspectives to put primary literature in context Includes integrated recommended reading references within each chapter Provides access to online ancillary package inclusive of annotated PowerPoint images, instructor’s manual, study guide, and test bank