Handbook Of Magnetic Resonance Spectroscopy In Vivo

This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

Isolated Cells and Perfused Organs 1. O. Kaplan, P.C.M. van Zijl, J.S. Cohen, Washington, DC/USA NMR Studies of Metabolism of Cells and Perfused Organs Individual Nuclei 2. S.R. Williams, London, UK In Vivo Proton Spectroscopy: Experimental Asoects and Potential 3. N. Beckmann, Basel, Switzerland In Vivo 13C Spectroscopy in Humans 4. M.J.W. Prior, R.J. Maxwell, J.R. Griffiths, London, UK Fluorine - 19F NMR Spectroscopy and Imaging In Vivo 5. J.S. Ingwall, Boston, MA/USA Measuring Cation Movements Across the Cell Wall Using NMR Spectroscopy: Sodium Movements in Striated Muscle 6. M. Rudin, A. Sauter, Basel, Switzerland In Vivo Phosphorus-31 NMR: Potential and Limitations.

Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches

In Vivo NMR Spectroscopy Robin A. de Graaf Department of in vivo NMR, Utrecht University, The Netherlands This is the first book in the field of in vivo NMR to cover in depth the technical and basic biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The book has also a practical setup, allowing readers to incorporate the presented concepts into their own MR research. An extensive treatment of radiofrequency pulses is given, together with several tables and recipes for their generation. A practical approach is followed in describing spatial localization and the pros and cons of all known water-suppression techniques. In addition, 2-D NMR, magnetic resonance imaging, spectroscopic imaging, spectral editing and many basic principles are explained and illustrated using practical examples. Several tables containing basic biophysical information, such as resonance frequencies, diffusion coefficients, relaxation constants, and absolute concentrations are also presented. The educational and practical character of this book makes it ideal for use in training courses at large research institutes and academic hospitals. In general, all those involved in fundamental and/or diagnostic in vivo NMR will find this book useful. This can range from people working in dedicated in vivo NMR institutes to radiologists working in hospitals. Also, those who want to broaden their knowledge on the concepts of NMR, such as researchers in high-resolution NMR, neurology, physiology, chemistry, and medical biology will benefit greatly from this book.

Magnetic resonance spectroscopy (MRS) has been an important analytical tool in organic chemistry, biology, and materials science for more than a half-century. Now, recent advances in the clinical application of MRS are allowing radiologists to more effectively diagnose lymphoma, head and neck cancers, and brain tumors, as well as to understand metabolic brain anomalies such as stroke and dementia. Clinical MR Spectroscopy: First Principles acquaints readers with the basic physics and chemistry of MRS while providing clear, practical guidelines for its clinical use. While most readers are likely to have had experience with MRI, this is not a prerequisite for understanding either the basic science or applied sections of the book. Individual chapters address such topics as: * The basic concepts of MRS * Hardware and software requirements * Techniques for localized spectroscopy * Spectroscopy data processing * The application of MRS in examining the brain, heart, muscles, and liver. Clinical MR Spectroscopy: First Principles features numerous line drawings to clarify the basic science of MRS and images to illustrate its clinical utility. This concise and timely book provides an accessible but comprehensive resource for radiologists, MRI technologists, and radiology residents.