Too Much Blood

This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri’s Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today’s medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

It is a quiet, uneventful Saturday in Doncaster. Nick Aten, and his best friend Steve Price – troubled seventeen year olds – spend it as usual hanging around the sleepy town, eating fast food and planning their revenge on Tug Slatter, a local bully and their arch-enemy. But by Sunday, Tug Slatter becomes the last of their worries because somehow overnight civilization is in ruins. Adults have become murderously insane – literally. They're infected with an uncontrollable urge to kill the young. Including their own children. As Nick and Steve try to escape the deadly town covered with the mutilated bodies of kids, a group of blood-thirsty adults ambushes them. Just a day before they were caring parents and concerned teachers, today they are savages destroying the future generation. Will Nick and Steve manage to escape? Is their hope that outside the Doncaster borders the world is 'normal' just a childish dream? Blood Crazy, first published in 1995, is a gripping, apocalyptic horror from Simon Clark.

A standard blood test indicates how well the kidneys and liver are functioning, the potential for heart disease, and a host of other vital health markers. Unfortunately, most of us cannot decipher these results ourselves, nor can we even formulate the right questions to ask about them—or we couldn’t until now. In Your Blood Never Lies, best-selling author James LaValle clears up the mystery surrounding blood test results. In simple language, he explains all of the information found on these forms, making it understandable and accessible. This means that you can look at the results yourself and know the significance of each marker. Dr. LaValle even recommends the most effective conventional and complementary treatments for dealing with any problematic findings. Rounding out the book are the names of test markers that should be requested for a more complete physical picture. A blood test can reveal so much about your body, but only if you can interpret the results. Your Blood Never Lies provides the up-to-date information you need to take control of your health.

Selected for The Globe 100 Books in 2013. With the 2013 CBC Massey Lectures, bestselling author Lawrence Hill offers a provocative examination of the scientific and social history of blood, and on the ways that it unites and divides us today. Blood runs red through every person’s arteries and fulfills the same functions in every human being. The study of blood has advanced our understanding of biology and improved medical treatments, but its cultural and social representations have divided us perennially. Blood pulses through religion, literature, and the visual arts. Every time it pools or spills, we learn a little more about what brings human beings together and what pulls us apart. For centuries, perceptions of difference in our blood have separated people on the basis of gender, race, class, and nation. Ideas about blood purity have spawned rules about who gets to belong to a family or cultural group, who enjoys the rights of citizenship and nationality, what privileges one can expect to be granted or denied, whether you inherit poverty or the right to rule over the masses, what constitutes fair play in sport, and what defines a person’s identity. Blood: The Stuff of Life is a bold meditation on blood as an historical and contemporary marker of identity, belonging, gender, race, class, citizenship, athletic superiority, and nationhood.

Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).

Comprehensive and up-to-date clinical reference, with an emphasis on treatment.