The Ventilator Project

A raging pandemic, a dearth of life-saving equipment, and ninety days to manufacture a world-class ventilator. On 24 March 2020, a nationwide lockdown was imposed in India in the face of a formidable adversary, the Covid-19 pandemic. With the number of cases increasing exponentially, hospitals were faced with a dangerous shortage of life-saving equipment and personnel. In response to the imminent crisis, Amitabha Bandyopadhyay and Srikant Sastri formed the IIT Kanpur ventilator Consortium as a task force to assist a young startup, Nocca Robotics, in building affordable high-quality ventilators for India’s cash-strapped hospitals. Under the mentorship of reputed industry leaders, the task force and the Nocca team worked tirelessly against unprecedented odds – trammelled by a ban on imports and telecommuting through Zoom and Whatsapp in the face of stringent lockdown restrictions – to manufacture the Noccarc V310 in record time. This is the incredible story of its conception, creation and success, in the words of the task force co-leaders themselves. Inspiring and riveting, The Ventilator Project also offers an unmatched blueprint for business in the post-Covid era through first-hand lessons gleaned during the task force’s phenomenal ninety-day run. It proves that India, with its deep recesses of talent and ingenuity, has the potential to be a world leader in both business and social impact.

This guideline defines ventilation and then natural ventilation. It explores the design requirements for natural ventilation in the context of infection control, describing the basic principles of design, construction, operation and maintenance for an effective natural ventilation system to control infection in health-care settings.

Practical clinical handbook reviewing all aspects of the diagnosis and management of intra-abdominal hypertension; essential reading for all critical care staff.

A practical application-based guide to adult mechanical ventilation This trusted guide is written from the perspective of authors who have more than seventy-five years' experience as clinicians, educators, researchers, and authors. Featuring chapters that are concise, focused, and practical, this book is unique. Unlike other references on the topic, this resource is about mechanical ventilation rather than mechanical ventilators. It is written to provide a solid understanding of the general principles and essential foundational knowledge of mechanical ventilation as required by respiratory therapists and critical care physicians. To make it clinically relevant, Essentials of Mechanical Ventilation includes disease-specific chapters related to mechanical ventilation in these conditions. Essentials of Mechanical Ventilation is divided into four parts: Part One, Principles of Mechanical Ventilation describes basic principles of mechanical ventilation and then continues with issues such as indications for mechanical ventilation, appropriate physiologic goals, and ventilator liberation. Part Two, Ventilator Management, gives practical advice for ventilating patients with a variety of diseases. Part Three, Monitoring During Mechanical Ventilation, discusses blood gases, hemodynamics, mechanics, and waveforms. Part Four, Topics in Mechanical Ventilation, covers issues such as airway management, aerosol delivery, and extracorporeal life support. Essentials of Mechanical Ventilation is a true “must read” for all clinicians caring for mechanically ventilated patients.

This book presents various practical breakthroughs of 3D printing (3DP) technologies in developing different types of tool and gadgets to be used against COVID-19 pandemic. It presents multidisciplinary aspects of 3DP technology in social, medical, administration, and scientific areas. This book presents state-of-the-art applications of 3DP technology in the development of PPE, ventilators, respiratory equipments, and customized drugs. It provides a comprehensive collection of the technical notes, research designs, literature prospective, and clinical applications of 3DP technologies to effectively deal with the COVID-19 pandemic. This book will be beneficial for the medical professionals, pharmacists, manufacturing enterprises, and young scholars in understanding the real potential of 3DP technologies in aiding humans-based activities against the COVID-19 crisis. Having interdisciplinary applications in applied science, this book will also be useful for wide range of academicians, research scholars and industry stakeholders.

Dinesh C. Sharma is a New Delhi-based award-winning journalist and author with over thirty-five years’ of professional experience. He has written extensively on science and technology, climate change, health, environment and innovation for national and international media, including The Lancet and Wired. He has been Science Editor at Mail Today, and Managing Editor at India Science Wire and is currently the Jawaharlal Nehru Fellow (2020-2021). His book The Outsourcer: The Story of India’s IT Revolution was awarded the Computer History Museum Book Prize in 2016. He has also been a visiting faculty at the Jawaharlal Nehru University, New Delhi and Ateneo de Manila University, Manila. Dinesh Sharma tweets at @dineshcsharma

The 5th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2022) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. Computational methodologies for implementation on the discovery of biomarkers for neurodegenerative diseases are extensively discussed. This volume focuses on the sessions from the conference regarding computational biology and bioinformatics.

A modern quantitative study of lung mechanics, relating mathematical modeling and engineering principles to lung function, structure, mechanics, and disease.

Medical Ventilator System Basics: A clinical guide is a user-friendly guide to the basic principles and the technical aspects of mechanical ventilation and modern complex ventilator systems. Designed to be used at the bed side by busy clinicians, this book demystifies the internal workings of ventilators so they can be used with confidence for day-to-day needs, for advanced ventilation, as well as for patients who are difficult to wean off the ventilator. Using clear language, the author guides the reader from pneumatic principles to the anatomy and physiology of respiration. Split into 16 easy to read chapters, this guide discusses the system components such as the ventilator, breathing circuit, and humidifier, and considers the major ventilator functions, including the control parameters and alarms. Including over 200 full-colour illustrations and practical troubleshooting information you can rely on, regardless of ventilator models or brands, this guide is an invaluable quick-reference resource for both experienced and inexperienced users.