The Spark Of Life Electricity In The Human Body

"This is a wonderful book. Frances Ashcroft has a rare gift for making difficult subjects accessible and fascinating." —Bill Bryson, author of The Body: A Guide for Occupants What happens during a heart attack? Can someone really die of fright? What is death, anyway? How does electroshock treatment affect the brain? What is consciousness? The answers to these questions lie in the electrical signals constantly traveling through our bodies, driving our thoughts, our movements, and even the beating of our hearts. The history of how scientists discovered the role of electricity in the human body is a colorful one, filled with extraordinary personalities, fierce debates, and brilliant experiments. Moreover, present-day research on electricity and ion channels has created one of the most exciting fields in science, shedding light on conditions ranging from diabetes and allergies to cystic fibrosis, migraines, and male infertility. With inimitable wit and a clear, fresh voice, award-winning researcher Frances Ashcroft weaves together compelling real-life stories with the latest scientific findings, giving us a spectacular account of the body electric.

We are all familiar with the idea that machines are powered by electricity, but perhaps not so aware that this is also true for ourselves. The Spark of Lifeis a spectacular account of the body electric, showing how, from before conception to the last breath we draw, electrical signals in our cells are essential to everything we think and do. These signals are produced by some amazing proteins that sit at the forefront of current scientific research - the ion channels. They are found in every cell in Earth and they govern every aspect of our lives, from consciousness to sexual attraction, fighting infection, our ability to see and hear, and the beating of our hearts. Ion channels are truly the 'spark of life'. Award-winning physiologist Frances Ashcroft weaves real-life stories with the latest scientific findings to explain the fundamental role of ion channels in our bodies. What happens when you have a heart attack? Why does an electric eel not shock itself? Can someone really die of fright? Why does Viagra turn the world blue? How do cocaine, LSD and morphine work? Why do chilli peppers taste hot? How do vampire bats sense their prey? Was Mary Shelley right when she inferred that electricity is the 'Spark of Life? Frances Ashcroft explains all this and more with wit and clarity. She introduces a cast of extraordinary personalities whose work has charted the links between molecule and mind over the centuries. She recounts the scientific detective stories involved in the development of our ideas about animal electricity, and shows how these are intimately entwined with our understanding of electricity itself. And she describes how the latest advances have led to the identification, and in some cases the cure, of a new class of disease. Anyone who has ever wondered about what makes us human will find this book a revelation.

'A wonderful book' Bill Bryson 'Ashcroft achieves the sort of rich simplicity most science writers can only dream about ... this book carries the eponymous spark of life' Sunday Telegraph From before birth to the last breath we draw, from consciousness to sexual attraction, fighting infection to the beating of our hearts, electricity is essential to everything we think and do. In The Spark of Life award-winning physiologist Frances Ashcroft reveals the secrets of ion channels, which produce the electrical signals in our cells. Can someone really die of fright? How do cocaine, LSD and morphine work? Why do chilli peppers taste hot? Ashcroft explains all this and more with wit and clarity. Anyone who has ever wondered about what makes us human will find this book a revelation. 'A rare gift for making difficult subjects accessible and fascinating' Bill Bryson 'She communicates complex science with engaging passion and eloquence' Helen Dunmore, Observer 'Compelling and very readable, an excellent writer' Literary Review 'Riveting ... she has a stock of good tales' New Scientist 'Lively, conversational prose, refreshingly accessible to any lay reader ... a positively charged little book' Daily Telegraph Frances Ashcroft is Professor of Physiology at the University of Oxford and a Fellow of Trinity College Oxford. She is also Director of OXION, a consortium of scientists studying ion channels, the heroes of this book. Her scientific research focuses on how a rise in your blood sugar level stimulates the release of insulin and what why this process goes wrong in diabetes. She has won many prizes for her research, most recently the L'Oreal/UNESCO 2012 Women in Science award. She is also a recipient of the Lewis Thomas Prize for Science Writing for The Spark of Life. Her first book for the general reader was Life at the Extremes: The Science of Survival.

A fresh look at electricity and its powerful role in life on Earth When we think of electricity, we likely imagine the energy humming inside our home appliances or lighting up our electronic devices—or perhaps we envision the lightning-streaked clouds of a stormy sky. But electricity is more than an external source of power, heat, or illumination. Life at its essence is nothing if not electrical. The story of how we came to understand electricity’s essential role in all life is rooted in our observations of its influences on the body—influences governed by the body’s central nervous system. Spark explains the science of electricity from this fresh, biological perspective. Through vivid tales of scientists and individuals—from Benjamin Franklin to Elon Musk—Timothy Jorgensen shows how our views of electricity and the nervous system evolved in tandem, and how progress in one area enabled advancements in the other. He explains how these developments have allowed us to understand—and replicate—the ways electricity enables the body’s essential functions of sight, hearing, touch, and movement itself. Throughout, Jorgensen examines our fascination with electricity and how it can help or harm us. He explores a broad range of topics and events, including the Nobel Prize–winning discoveries of the electron and neuron, the history of experimentation involving electricity’s effects on the body, and recent breakthroughs in the use of electricity to treat disease. Filled with gripping adventures in scientific exploration, Spark offers an indispensable look at electricity, how it works, and how it animates our lives from within and without.

Explores the limits of human survival and the physiological adaptations that enable us to exist under extreme conditions. The author reviews limits to human life underwater, at high altitudes, at high speeds, at micro levels, and at freezing and hot temperatures.

Why can salamanders grow new legs, and young children grow new finger tips, but adult humans can't regenerate? What is the electricity that flows through the human body? Is it the same thing that the Chinese call Qi? If so, what does Chinese medicine know, that western medicine ignores? Dan Keown's highly accessible, witty, and original book shows how western medicine validates the theories of Chinese medicine, and how Chinese medicine explains the mysteries of the body that western medicine largely ignores. He explains the generative force of embryology, how the hearts of two people in love (or in scientific terms `quantum entanglement') truly beat as one, how a cheating heart is also an ill heart (which is why men are twice as likely to die of a sudden heart attack with their mistress than with their wife), how neural crest cells determine our lifespan, and why Proust's madeleines evoked the memories they did. The book shows how the theories of western and Chinese medicine support each other, and how the integrated theory enlarges our understanding of how bodies work on every level. Full of good stories and surprising details, Dan Keown's book is essential reading for anyone who has ever wanted to know how the body really works.

This "utterly spectacular" book weighs the impact modern medical technology has had on the author's life against the social and environmental costs inevitably incurred by the mining that makes such innovation possible (Rachel Louise Snyder, author of No Visible Bruises). What if a lifesaving medical device causes loss of life along its supply chain? That's the question Katherine E. Standefer finds herself asking one night after being suddenly shocked by her implanted cardiac defibrillator. In this gripping, intimate memoir about health, illness, and the invisible reverberating effects of our medical system, Standefer recounts the astonishing true story of the rare diagnosis that upended her rugged life in the mountains of Wyoming and sent her tumbling into a fraught maze of cardiology units, dramatic surgeries, and slow, painful recoveries. As her life increasingly comes to revolve around the internal defibrillator freshly wired into her heart, she becomes consumed with questions about the supply chain that allows such an ostensibly miraculous device to exist. So she sets out to trace its materials back to their roots. From the sterile labs of a medical device manufacturer in southern California to the tantalum and tin mines seized by armed groups in the Democratic Republic of the Congo to a nickel and cobalt mine carved out of endemic Madagascar jungle, Lightning Flowers takes us on a global reckoning with the social and environmental costs of a technology that promises to be lifesaving but is, in fact, much more complicated. Deeply personal and sharply reported, Lightning Flowers takes a hard look at technological mythos, healthcare, and our cultural relationship to medical technology, raising important questions about our obligations to one another, and the cost of saving one life.

Tap into the extraordinary power of electricity to heal your body and empower your life Everything is electric. This seemingly simple observation has transformational repercussions on the way we think about and approach physical, mental, and emotional health. Electric Body, Electric Health is a manifesto for personal empowerment based on an electrical view of life. Author of Tuning the Human Biofield, Eileen Day McKusick is an expert in the emerging field of electric health and has taught thousands how to transform effortlessly through learning to “think electrically.” By illuminating the biological nature of our electrical bodies, McKusick empowers readers to clear the static, noise, and resistance from this system and experience greater energy, clarity, and order. Electric Body, Electric Health makes use of simple, easy-to-implement practices such as: - Awareness practices - Perspective shifts - Breathing practices - Simple lifestyle changes - Improved emotional management - and more... in order to help readers improve their health and enhance their daily lives. It will give you the tools to transform your relationship with your body, your mind, your emotions, and the electrical world around you.

From the invention of the telegraph to the discovery of X rays, Simon has created a revealing portrait of an anxious age when Americans welcomed electricity into their bodies even as they kept it from their homes.

The story of a neural impulse and what it reveals about how our brains work We see the last cookie in the box and think, can I take that? We reach a hand out. In the 2.1 seconds that this impulse travels through our brain, billions of neurons communicate with one another, sending blips of voltage through our sensory and motor regions. Neuroscientists call these blips “spikes.” Spikes enable us to do everything: talk, eat, run, see, plan, and decide. In The Spike, Mark Humphries takes readers on the epic journey of a spike through a single, brief reaction. In vivid language, Humphries tells the story of what happens in our brain, what we know about spikes, and what we still have left to understand about them. Drawing on decades of research in neuroscience, Humphries explores how spikes are born, how they are transmitted, and how they lead us to action. He dives into previously unanswered mysteries: Why are most neurons silent? What causes neurons to fire spikes spontaneously, without input from other neurons or the outside world? Why do most spikes fail to reach any destination? Humphries presents a new vision of the brain, one where fundamental computations are carried out by spontaneous spikes that predict what will happen in the world, helping us to perceive, decide, and react quickly enough for our survival. Traversing neuroscience’s expansive terrain, The Spike follows a single electrical response to illuminate how our extraordinary brains work.