The Clinical Neuroscience Of Lateralization

The Clinical Neuroscience of Lateralization gives the first comprehensive transdiagnostic overview of the evidence for changes in hemispheric asymmetries in different psychiatric and neurodevelopmental disorders. Taking a multidisciplinary perspective informed by both basic science and clinical studies, the authors integrate recent breakthroughs on hemispheric asymmetries in psychology, neuroscience, genetics and comparative research. They give a general introduction to hemispheric asymmetries and the techniques used to assess them, and review the evidence for changes in hemispheric asymmetries in different psychiatric and neurodevelopmental disorders. The book also discusses neurological disorders like Parkinson’s disease and multiple sclerosis and highlights the importance of open science in clinical laterality research. Offering a fresh perspective on a longstanding issue in clinical neuroscience, this book will be of great interest for academics, researchers, and students in the fields of clinical and developmental neuroscience, biopsychology and neuropsychology.

Cerebral Lateralization in Nonhuman Species explores brain asymmetries in animals and the extent to which such asymmetries relate, in an evolutionary and clinical sense, to the pervasive asymmetries that characterize the human brain. Topics covered include cerebral lateralization in birds, rats, and nonhuman primates; the inheritance of direction and degree of asymmetry in the brain; the morphology of rat forebrain; and variation in the pattern of behavioral and brain asymmetries due to sex differences. Comprised of 11 chapters, this book opens with a historical overview of research into the cerebral lateralization of structures and functions in nonhuman species. The discussion then turns to lateralization of vocal control in songbirds and lateralization of several behaviors in domestic chicks. The inheritance of direction and degree of asymmetry is also considered, along with the morphology of rat forebrains. The following chapters focus on asymmetries in anatomy and pathology in the rodent brain; the link between brain lateralization and behavioral functions; and how early experiences can induce laterality. The final chapter analyzes the implications of brain asymmetries for evolution, genetics, and clinical syndromes. This monograph will be a useful resource for students, neuroscientists, clinicians, and other practitioners in fields ranging from psychobiology and psychology to anatomical sciences, neurobiology, neurochemistry, and genetics.

The second edition of The Lateralized Brain provides for readers a volume detailing the functional and structural differences between the left and right hemispheres of the brain, highlighting how the widespread use of modern neuroimaging techniques such as fMRI and DTI have completely changed the way hemispheric asymmetries are currently investigated. In this new edition, all chapters have been updated with recent advances in the field, and a new chapter on hemispheric asymmetries in development and aging has been integrated. Also featured is a new, larger section on laterality in social behavior, alongside a comprehensive overview about key topics in laterality research, including its history, evolutionary perspectives, brain structure, and the role of the corpus callosum. Chapters cover functional hemispheric asymmetries in language processing, motor behavior, spatial attention, self- and face-perception, emotion processing, and social behavior. Additional topics include the ontogenesis of hemispheric asymmetries and their development over the life span, as well as sex differences and associations with clinical syndromes. This volume can be used by anyone working on hemispheric biology or in courses on hemispheric asymmetries. Provides a comprehensive overview about key topics in laterality research, including its history, evolutionary perspectives, the corpus callosum, and brain structure Includes references to key articles, books, protocols, and online resources for additional, detailed study Discusses classic studies that helped define the field of laterality research and presents introductory short stories (e.g. famous classic clinical cases in laterality research) as a starting point for each chapter Covers key concepts and methods in separate call-out boxes for quick overview Newly integrates a chapter on laterality in social behavior, as well as various smaller new sections covering recent advances in the field

Brain Laterality answers one of the major questions we ask ourselves every day: where? The book provides a thematic, comprehensive overview of the brain mechanisms that influence whether we go to the left or right, on which side we stand, and which hand we use. Covering a broad range of topics, including handedness, apraxia, and motor control, alongside theories of emotion, creativity, and genetics, the book condenses a vast amount of research from multiple fields into a concise and entertaining read. Featuring anecdotes from the author's own illustrious research and clinical career, this book is a must-read for psychology students, neuropsychologists, neurologists, and anyone interested in the brain's role in handedness, directional movement, intention, action, and posturing.

Laterality: Functional Asymmetry in the Intact Brain focuses on brain function and laterality as well as the various methods in assessing behavioral asymmetries, including handedness. It reviews the literature on perceptual-cognitive laterality effects in different sensory modalities, the lateralization of emotion and motor behavior, and the electrophysiological evidence. It also highlights some of the problems with the existing research and offers suggestions about the direction of future research. Organized into 17 chapters, this volume begins with an overview of cerebral asymmetry and the origins and mechanisms of lateralization. Then, it discusses the individual differences in laterality, methods and measurement used in laterality studies, and experiments on dichotic listening and auditory lateralization. The next chapters focus on the link between verbal laterality and handedness, tactual and perceptual laterality, asymmetry of motor performance, lateralization of emotional processes, and physiological measures of asymmetry. The book also introduces the handedness and its relation to cerebral function, genetics of laterality, development of cerebral lateralization, individual differences in cerebral organization, sex differences in laterality, reading- and language-related deficits, and control of the active hemisphere before concluding with a chapter discussing the experimental or strategy effects, the concept of complementary specialization, and the dichotomy between the two hemispheres of the brain. This book is a valuable resource for neuropsychologists, experimental psychologists, neurologists, and educators interested in understanding human brain function.

Lateralization in the Nervous System reviews various aspects of lateralization in the nervous system, with emphasis on approaches such as the investigation of turning tendencies and electrocortical indices of hemispheric asymmetry. Experimental paradigms and outcomes that are applicable to both human and nonhuman species are highlighted. This book is comprised of 26 chapters and begins with an overview of functional lateralization in nonhuman species such as monkeys. Brain asymmetry is examined in context with other biological asymmetries in the quest for general mechanisms and principles of lateralization. The problem of inheritance, embryology, and development of asymmetry is also discussed from a variety of environmentalist and nativist perspectives. Highly suggestive invertebrate and avian models for lateralization are presented, along with the evidence for cerebral dominance and handedness in nonhuman species. Human clinical neuropsychological findings, such as the effects of unilateral cortical and thalamic lesions and the syndrome of unilateral neglect, are considered, together with asymmetries in perception and attention. This monograph will be of interest to psychologists (physiological, cognitive, developmental, and clinical), behavioral biologists, neuroscientists, neurologists, and psychiatrists, as well as to scholars and educators from the humanities and social sciences who are concerned with the nature and biological bases of left-right differences in brain, behavior, and thinking.

First Published in 1991. Routledge is an imprint of Taylor & Francis, an informa company.

Left-right asymmetries of structure and function are a common organization principle in the brains of humans and non-human vertebrates alike. While there are inherently asymmetric systems such as the human language system or the song system of songbirds, the impact of structural or functional asymmetries on perception, cognition and behavior is not necessarily limited to these systems. For example, performance in experimental paradigms that assess executive functions such as inhibition, planning or action monitoring is influenced by information processing in the bottom-up channel. Depending on the type of stimuli used, one hemisphere can be more efficient in processing than the other and these functional cerebral asymmetries have been shown to modulate the efficacy of executive functions via the bottom-up channel. We only begin to understand the complex neuronal mechanisms underlying this interaction between hemispheric asymmetries and cognitive systems. Therefore, it is the aim of this Research Topics to further elucidate how structural or functional hemispheric asymmetries modulate perception, cognition and behavior in the broadest sense.

Human Laterality presents the main facts of human laterality as they are known. Drawing on evidence from normal, intact human beings and neurological patients, along with material on asymmetries in other species, this book traces the development of laterality, its evolution, and inheritance. This text also reviews the literature on the relation between laterality and developmental disorders of speech and language, including dyslexia, stuttering, and dysphasia. This book is organized into nine chapters and begins with an overview of the development of knowledge and ideas about laterality over the course of history. This text gives an account of the myths that abound regarding handedness, including the association of right with male and left with female, with the goal of demythologizing human laterality. It argues that there is a common basis to both handedness and cerebral lateralization, and indeed to other manifestations of human laterality such as eyedness and footedness, and that lateralization is fundamentally biological rather than sociocultural. Human laterality is also seen as an innate disposition rather than a matter of learning or imitation. In the final chapter, this book speculates about the possible origins of laterality in the fundamental asymmetries of living molecules and of particle physics. This book is essential reading for biologists and researchers interested in the human anatomy.

Clinical neuroscience refers to a subfield of neuroscience which focuses on the scientific study of fundamental mechanisms that underly disorders and diseases of the central nervous system and brain. It aims to develop new methods of conceptualizing and diagnosing such disorders and developing new therapies. The human nervous system is divided into two symmetric halves, but a closer examination of the brain reveals functional and anatomical lateralization. Brain asymmetry is detected in terms of behavior, structure and function. Experiential, evolutionary, genetic, developmental and pathological factors are hypothesized to have a role in this lateralization. Defects in brain asymmetry are linked to a variety of neurological disorders, and certain disorders exacerbate the brain asymmetries. Various disorders related with brain asymmetries include schizophrenia and dyslexia. This book explores all the important aspects of brain aging in the present day scenario. Those with an interest in this field would find it helpful.