Testicular Cancer

This encompassing book is designed to contribute to a teamwork approach by promoting understanding between radiologists and clinical oncologists. All of the currently available imaging modalities of relevance in clinical oncology are covered, and the presentation of a broad spectrum of oncologic diseases (of most organ systems) on these modalities is discussed and illustrated. The role of multiparametric and multimodality imaging approaches providing both morphologic and functional information is considered in detail, and careful attention is paid to the latest developments in higher field (3T) MR imaging and advanced MR techniques such as diffusion-weighted imaging, diffusion tensor imaging, perfusion-weighted imaging and spectroscopy. The major challenge of incorporating progress in quantitative imaging technology into radiotherapy treatment planning, guidance, and monitoring is also addressed. This book will assist in refining the treatment approach in various oncologic diseases and organ systems based on specific imaging features. It will be of value to radiologists, oncologists, and other medical professionals involved in the diagnosis and treatment of oncology patients. ​

EWAN CAMERON IS A VANCOUVER-BASED HEALTH RESEARCHER THAT HAS UNCOVERED THE TRUTH ABOUT TESTICULAR CANCER AND HOW THE PHARMACEUTICAL INDUSTRY HAS KEPT THIS HIDDEN FROM THE PUBLIC. A GRADUATE OF THE NORTHERN ALBERTA INSTITUTE OF TECHNOLOGY, HE COMPLETED HIS JOURNALISM STUDIES IN THE EARLY 2000'S BEFORE JOINING A LOCAL NEWSPAPER, WHERE HE BECAME DISILLUSIONED BY HIS EDITOR'S REFUSAL TO PUBLISH HEALTH-RELATED AND POLLUTION-RELATED NEWS STORIES. THE REASON? THEY WOULD UPSET THEIR CORPORATE CLIENTS ON WHICH THE NEWSPAPER DEPENDED FOR ADVERTISING REVENUE. AFTER SETTING UP HIS OWN BLOG AND PUBLISHING MORE THAN THIRTY HEALTH-RELATED BOOKS UNDER A PEN NAME, EWAN WAS CONTACTED BY A WHISTLEBLOWER WORKING AT A U.S. PHARMACEUTICAL COMPANY. SOME OF THE EXPLOSIVE MATERIAL HE REVEALED IS CONTAINED IN THE PAGES OF THIS BOOK. IN THIS EXPLOSIVE EXPOS , EWAN CAMERON REVEALS: - HOW TO HEAL YOURSELF NATURALLY OF TESTICULAR CANCER - STORIES OF ORDINARY PEOPLE WHO CURED THEMSELVES OF TESTICULAR CANCER NATURALLY - WHY THE QUALITY OF YOUR HEALTH DEPENDS ON THE QUALITY OF YOUR CELLS - HOW TESTICULAR CANCER STARTS FIRST IN THE MIND - 33 FACTS VACCINE COMPANIES DON'T WANT YOU TO KNOW - THE 7 TOXIC FOODS ON YOUR FAMILY'S DINNER TABLE - 17 NATURAL CANCER REMEDIES "THEY" DON'T WANT YOU TO KNOW ABOUT - THE TRUTH ABOUT WHAT REALLY CAUSES TESTICULAR CANCER - HOW TO LIVE TO 100 AND BEYOND - LITTLE-KNOWN LONGEVITY SECRETS - THE 21 TOXIC CHEMICALS IN YOUR HOME & BATHROOM - HOW TO REGAIN YOUR HEALTH NATURALLY & RAPIDLY - ACTIONS YOU CAN TAKE RIGHT NOW TO HEAL FROM TESTICULAR CANCER ...AND MUCH, MUCH MORE

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!

Testicular and Penile Cancer outlines the initial surgical approaches and treatment options such as chemotherapy and radiation for patients with these diseases. It is a practical guide providing epidemiological, diagnostic and therapeutic management details to faciliate optimal treatment of testicular and penile cancers.

The testicles are a man's most sensitive body region. Unusual observations and sensations in this area such as pain, swelling, and lumps are very disquieting and often raise concerns as to whether these could be signs of testicular cancer. This book is an essential guide for people with such symptoms and subsequent concerns. In an easy to understand language, the experienced health author Dr. Rupert B. Hansen explains the symptoms, causes, diagnoses, and effective treatments of the most common testicle health problems such as testicular pain, swelling, trauma, infection, testicular torsion, lumps, cysts, spermatocele, varicocele, hernia, and testicular cancer. In addition to the standard treatments for each of these conditions, complementary therapeutic options such as homeopathy, Ayurveda, oxygen therapy, specific diets, and many more are also presented and discussed. Put your worries behind you! This essential patient guide full of sound information supports you in calming down and making informed decisions on your path back to testicular health.

A must-have reference, this new edition provides practical information on treatment guidelines, details of diagnosis and therapy, and personal recommendations on patient management from experts in the field. Consistently formatted chapters allow for a user-friendly presentation for quick access of key information by the practicing clinician. Completely updated, this new edition includes all of the latest developments in treatment strategies of medical, surgical and radiation oncologists.

Testicular cancer (TC) is the most common cancer in males aged 20-40 years, with a worldwide incidence of 7.5 per 100,000, but the rates vary considerably between countries and ethnic groups and there is evidence also for an increasing incidence in last decades. About 95% of all TCs are represented by testicular germ cell tumors (TGCTs), which include seminoma and non-seminoma histological types. It is generally assumed that the development of TGCT is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested genetic association of TGCT with variations in genes involved in hypothalamic-pituitary-testicular axis and steroidogenic enzymes. This recent evidence expands the current knowledge on the role of genetic contribution in testicular cancer susceptibility, and supports the hypothesis that variations in hormone metabolism genes might change the hormonal environment implicated in testicular carcinogenesis. Therefore, hormonal carcinogenesis is an important and controversial area of current research in TGCT, and further attention is given to genetic factors influencing hormone-related cancer risk. The genetic component to TGCT is in general strong. In fact, although environmental factors clearly contribute to TGCT development (and probably to its increasing incidence in some geographical areas), the proportion of TGCT susceptibility accounted for by the genetic effects is estimated at 25%. TGCT has high familial risks compared with most other cancer types that are generally no more than two-fold: brothers of individuals with TGCT have an 8- to 12-fold increased risk of disease, and sons of affected individuals have a 4- to 6-fold increased risk. Despite this strong familial relative risk, early results from linkage studies identified a limited relationship with genetic factors, suggesting that TGCT is a genetically complex trait. However, more recently, four genome-wide association studies (GWAS) from the UK and USA have reported association of TGCTs with six new loci (KITLG, SPRY4, BAK1, DMRT1, TERT, and ATF7IP). The strongest association for TGCT susceptibility was found for SNPs in KITLG (ligand for the membrane-bound receptor tyrosine kinase KIT) gene with a greater than 2.5-fold increased risk of disease per major allele, which is the highest reported for any cancer to date. These studies are being now replicated by other researches and attention is given to the relationship between these genetic variations, TGCT risk and frequently associated anomalies of the reproductive tract, such as cryptorchidism and infertility. Finally, over the past few decades, TCGT research has focused also on external environmental causes acting mainly as endocrine disrupters of androgen and oestrogen pathways, even during the foetal development of the testis. It is well known that the testicular dysgenesis syndrome (TDS) hypothesis, proposed ten years ago, suggests that disturbed testicular development in fetal life may result in one or more of four disorders postnatally, named cryptorchidism, hypospadias, poor semen quality, and TGCT. These four disorders are therefore considered as one clinical entity and are linked together by epidemiological and pathophysiological relations. The relative contribution of genetics and environment in TGCT development, and the interactions between endocrine disruptors and variations in genes involved in hormonal carcinogenesis is therefore another interesting area of research.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Discusses testicular cancer, providing information on what it is, diagnosis and treatment of the ailment, and how it affects one's life.