Studies On As Triazine Derivatives

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Different types of 2,4,6-Trichloro-[1,3,5]triazine derivatives were synthesized by using morpholine and different types of amines. The synthesized structures of these compounds were confirmed by Mass, IR and 1H NMR spectral analysis. The newly synthesized compounds were also evaluated for antimicrobial activity against variety of bacterial strains and some of these compounds have shown good antimicrobial activities.

1,3,5-Triazine derivatives find wide applications as bioactive compounds and drugs, components of polymer compositions, reactive dyes, energetic materials, reagents for organic synthesis, combinatorial and analytical chemistry. In this book, the authors present topical research in the study of the synthesis, applications and toxicity of triazines. Topics discussed include polynitromethyl 1-1,3,5 triazines; application of triazine based dendrimers as drug delivery agents; biodegradation of s-triazine herbicides in soil/surface water environments and synthesis and properties of heat-resistant polymers containing triaryl-s-triazine moiety.

The field referred to is that of the simplest 1,3,5-triazine derivatives, and specifically the 1,3,5-triazine C3H3N3 itself (that is, the symmetric cyclic trimer of hydrocyanic acid, the basic member of the class) together with its various homologs which form next to it the CnH2n-3N3 series. They are quite naturally divided into three metameric groups with 1, 2 or 3 alkyl radicals on the triazine ring.

Indazole, Pyrazole and s-Triazine derivatives possess Therapeutic and Pharmaceutical activity such as anti-inflammatory, anti-pyretic, anti-parasitic, anti-malarial, anti-bacterial and anti-fungal. In this book, we have reported how to synthesize compounds bearing Indazole, Pyrazole and s-Triazine. All the new reported compounds were characterized by elemental analysis, FT-IR, 1H NMR and Mass Spectroscopy. These compounds were found to be very good anti-bacterial and anti-fungal activity. This book is useful for any reserchers of Chemistry, Pharmacy or related disciplines who are familiar with synthesis of organic derivatives.

A procedure for studying the kinetics of the alkaline hydrolysis of 2-chloro-4,6-disubstituted symmetrical triazines was developed. The coefficients of the Arrhenius equation were determined for a number of triazine derivatives. An isokinetic relationship was found for the alkaline hydrolysis of monochloro derivative triazines. The possibility of applying the Hammett equation to the given class of compounds was shown in principle. (Author).