Structural And Biological Applications Of Schiff Base Metal Complexes

Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher’s interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system. In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff’s base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives. This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate. Features : This book would be useful for academia, researchers and engineers working in the area of Schiff base and their metal complexes. This book will give an in-depth account of the properties of Schiff base and their metal complexes. This book will discuss the details of synthesis methods for Schiff base and their metal complexes. This book will cover emerging trends in the use of Schiff base metal complexes in the industry. This book will provide an overview of the wider biological applications of Schiff base metal complexes

Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher’s interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system. In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff’s base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives. This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate. Features : This book would be useful for academia, researchers and engineers working in the area of Schiff base and their metal complexes. This book will give an in-depth account of the properties of Schiff base and their metal complexes. This book will discuss the details of synthesis methods for Schiff base and their metal complexes. This book will cover emerging trends in the use of Schiff base metal complexes in the industry. This book will provide an overview of the wider biological applications of Schiff base metal complexes

Schiff Base Metal Complexes Schiff bases are compounds created from a condensed amino compounds, which frequently form complexes with metal ions. They have diverse applications in biology, catalysis, material science and industry. Understanding these compounds, their properties, and the available methods for synthesizing them is a key to unlocking industrial innovation. Schiff Base Metal Complexes provides a comprehensive overview of these compounds. It introduces the compounds and their properties before discussing their various synthesizing methods. A survey of existing and potential applications gives a complete picture and makes this a crucial guide for researchers and industry professionals looking to work with Schiff base complexes. Schiff Base Metal Complexes readers will also find: A systematic and organized structure designed to make information instantly accessible Detailed coverage of thermal synthesis, photochemical synthesis, and more Challenges with different methods described in order to help readers make the correct choice for their own work Schiff Base Metal Complexes is a useful reference for organic chemists, materials scientists, and researchers or industry professionals working with organometallics.

A Schiff base (imine -N=CH-) is a part of a popular group of organic compounds prepared form primary amines and aldehyde. Many studies have been carried out on Schiff bases not only as organic compounds but also as ligands for metal complexes. In this context, this book provides a comprehensive, interdisciplinary review of Schiff base compounds, with an emphasis on the latest advances. It compiles research results, commentary, reviews, and more dealing with preparation, spectroscopy, crystallography, (asymmetric) synthetic roles, physical properties (magnets, optics, etc.), computational chemistry, and theoretical chemistry. The book focuses on Schiff base and its strong connection to organic chemistry, biochemistry, and polymer materials chemistry. It covers three topics: Schiff base of organic chemistry, Schiff base of inorganic chemistry, and Schiff base of functional or biological materials.

Schiff bases, originally introduced by German chemist Hugo Schiff in 1864, are well-known imine or azomethine (RR’C=NR”) moieties prepared from aldehydes and primary amines through condensation. Since then, Schiff bases have been recognized not only as compounds but also as useful ligands for metal complexes in inorganic coordination chemistry. This is because Schiff bases are essentially Lewis bases having lone pairs on the nitrogen (N) atom (M:N=CHR). In both organic and coordination chemistry, as well as related fields of science, the functions of Schiff base complexes and materials are of great interest. This book introduces and discusses novel aspects of Schiff base compounds.

The Beauty of Chemistry in the Words of Writers and in the Hands of Scientists, by Margherita Venturi, Enrico Marchi und Vincenzo Balzani Living in a Cage Is a Restricted Privilege, by Luigi Fabbrizzi Inner and Outer Beauty, by Kenneth N. Raymond und Casey J. Brown The Mechanical Bond: A Work of Art, by Carson J. Bruns und J. Fraser Stoddart The Beauty of Knots at the Molecular Level, by Jean-Pierre Sauvage und David B. Amabilino

Applications Transition metal complexes of acylhydrazones and related N, O donor Schiff bases and their metal complexes have attracted considerable attention during recent years because of their applications in several bio-chemical, industrial and analytical processes. Some of the applications of these compounds are mentioned below: As biological probes As optical devices As catalyst Mesogenic behavior As sensing material As DNA cleaving agents Super oxide dismutase-mimic activity In analytical processes Other uses The hydrazones have been used as plasticizers and stabilizers for polymers [Kuhn et al. (2001), Gupta et al. (2007)], polymerization initiators and antioxidants etc. Hydrazone compounds have the ability to control the release of volatile aldehydes and ketones [Levrand et al. (2006)]. The phenyl derivative Schiff bases have been used as corrosion inhibitors for aluminium in hydrochloric solution [Unaleroglu et al. (2001)]. It is apparent from the above applications that the selected field of transition metal complexes of N, O donor ligands is very useful and multi-dimensional. Each new ligand/ new complex or new study gives a new direction to the area of research.

A comprehensive treatise on the subject of Magnetochemistry. This is an essential textbook for those studying the subject and anyone interested in the magnetic properties of chemical compounds. Sections include: Part I: Measurement and Susceptibility. Part II: Atomic Diamagnetism. Part III: Molecular Diamagnetism. Part IV: Atomic Paramagnetism. Part V: Molecular Paramagnetism. Part VI: Complex Compounds. Part VII: Metallic Dia- and Paramagnetism. Part VIII: Ferromagnetism. Part IX: Applied Magnetism Analysis