Strategic And Technical Advisory Group On Antimicrobial Resistance Stag Amr Report Of Fifth Meeting

The World Health Organization (WHO) policy brief, "Antibacterial pipeline trends and recommendations to enhance research and development" provides recommendations to strengthen R&D for antibacterials based on current trends in the antibacterial pipeline, as part of a comprehensive effort to address persistent global health challenge posed by antimicrobial resistance (AMR). This WHO policy brief is based on the latest WHO pipeline report “2023 Antibacterial agents in clinical and preclinical development: an overview and analysis” (IRIS link) and is intended to serve as a tool for drug developers, policymakers and funders of research and development (R&D) in AMR and basic AMR research. The goal of this WHO policy brief is to guide the implementation of strategies to respond to persistent R&D challenges and strengthen the antibacterial pipeline. It highlights the continued urgent need for innovative drugs to combat drug-resistant infections, particularly against priority pathogens identified in the 2024 WHO Bacterial Priority Pathogen List (IRIS link) and other crucial gaps in the pipeline including drugs to address serious bacterial infections in the populations most affected, such as vulnerable patient populations. The WHO policy brief emphasizes global coordination and collaboration to advance R&D for antibacterial agents.

Organic Farming: Global Perspectives and Methods, Second Edition provides the core definition and concepts of organic farming, also addressing current challenges and goals. The book provides a comprehensive resource, from sustainability to influences on the ecosystem, including the significance of seed, soil, water and weed management, and other important aspects. In addition, it presents advancements in the field and insights on the future. This fully revised and updated edition expands coverage to include important economic considerations, understanding the influence of nanotechnology on organic farming, vertical farming, organic farming and livestock management, as well as the future of organic farming. Written by a team of global experts to provide current concepts of organic farming, this resource is valuable for researchers, graduate students, and post-doctoral fellows from academia and research institutions. Presents the latest insights, from basic principles to emerging practices and future prospects Includes new chapters on emerging organic farming practices and opportunities to address animal agriculture and vertical and indoor farming Includes coverage of standards, certification and accreditation, and presents insights on economics and marketing

The purpose of this manual is to provide guidance for countries on the methods and metrics for the surveillance of AMR in selected bacteria causing common human infections. This manual is part of a package of documents and tools designed to inform GLASS implementation and describes the objectives and methodology of GLASS AMR, the GLASS component dealing with the global surveillance of AMR in selected bacteria causing common human infections.

"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

While much progress has been made on achieving the Millenium Development Goals over the last decade, the number and complexity of global health challenges has persisted. Growing forces for globalization have increased the interconnectedness of the world and our interdependency on other countries, economies, and cultures. Monumental growth in international travel and trade have brought improved access to goods and services for many, but also carry ongoing and ever-present threats of zoonotic spillover and infectious disease outbreaks that threaten all. Global Health and the Future Role of the United States identifies global health priorities in light of current and emerging world threats. This report assesses the current global health landscape and how challenges, actions, and players have evolved over the last decade across a wide range of issues, and provides recommendations on how to increase responsiveness, coordination, and efficiency â€" both within the U.S. government and across the global health field.

On top of a decade of exacerbated disaster loss, exceptional global heat, retreating ice and rising sea levels, humanity and our food security face a range of new and unprecedented hazards, such as megafires, extreme weather events, desert locust swarms of magnitudes previously unseen, and the COVID-19 pandemic. Agriculture underpins the livelihoods of over 2.5 billion people – most of them in low-income developing countries – and remains a key driver of development. At no other point in history has agriculture been faced with such an array of familiar and unfamiliar risks, interacting in a hyperconnected world and a precipitously changing landscape. And agriculture continues to absorb a disproportionate share of the damage and loss wrought by disasters. Their growing frequency and intensity, along with the systemic nature of risk, are upending people’s lives, devastating livelihoods, and jeopardizing our entire food system. This report makes a powerful case for investing in resilience and disaster risk reduction – especially data gathering and analysis for evidence informed action – to ensure agriculture’s crucial role in achieving the future we want.

Freedom in the World, the Freedom House flagship survey whose findings have been published annually since 1972, is the standard-setting comparative assessment of global political rights and civil liberties. The survey ratings and narrative reports on 195 countries and fourteen territories are used by policymakers, the media, international corporations, civic activists, and human rights defenders to monitor trends in democracy and track improvements and setbacks in freedom worldwide. The Freedom in the World political rights and civil liberties ratings are determined through a multi-layered process of research and evaluation by a team of regional analysts and eminent scholars. The analysts used a broad range of sources of information, including foreign and domestic news reports, academic studies, nongovernmental organizations, think tanks, individual professional contacts, and visits to the region, in conducting their research. The methodology of the survey is derived in large measure from the Universal Declaration of Human Rights, and these standards are applied to all countries and territories, irrespective of geographical location, ethnic or religious composition, or level of economic development.