Penile Carcinoma

This book provides a comprehensive and state-of the-art approach to caring for penile carcinoma patients and provides foundational information related to the molecular pathways implicated in penile carcinogenesis and progression. Penile carcinoma remains one of the most debilitating and life-altering malignancies to affect men, with significant impacts on quality of life, erectile function/sexual activity, and length of life. This book illuminates recent advances in penile cancer sparing treatment approaches and oncologically appropriate therapeutic options that help to maintain quality of life, sexual function, and intimacy for patients. It also elucidates recent understandings of human papilloma virus (HPV) and non-HPV driven pathways, which are suspected to have distinct treatment responses and prognoses. The book explores the management of inguinal lymph nodes in the setting of penile cancer, which can now be managed with the integration of key surgical principles/techniques including the adoption of minimally invasive surgery. Considering a multidisciplinary treatment approach for patients exhibiting either locally advanced or more widespread metastatic disease, the book introduces novel systemic therapies currently in development. Further, this book raises clinician awareness of the significant psychosocial impact of penile carcinoma on patients and their families. Penile Carcinoma: Therapeutic Principles and Advances provides readers with the necessary knowledge and insight to care for penile cancer patients with the use of truly state-of-the-art diagnostic and therapeutic approaches. Cancer patients and their families will greatly benefit from adoption of these principles and the accessibility of such advances to their personalized care.

The aim of the updated book is to include new developments and update the literature in relation to sentinel node biopsy, new radiology techniques and long term epidemiological data. This book is useful for urologists, dermatologists, sexual health physicians as well as those with an interest in virology and genomics related to squamous cell cancers. The surgical techniques are all well illustrated with a step by step guide in order to allow those individuals in centres which are not expert centres to undertake the management of this devastating tumour.

Management of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.

This fully updated and revised second edition address specifically some of the significant advances made in our understanding of the pathophysiology of penile cancer including discussion of the suspected role of the human papilloma virus in penile carcinogenesis. Similarly, the molecular pathways implicated in precancerous and penile cancer will be discussed as these are the present targets of novel therapeutic approaches to this disease. The text details the recent national and international diagnostic and treatment guidelines that have been developed by both the National Comprehensive Cancer Network© and the European Urological Association establishing evidence based standards upon which the care of penile cancer should be based. The text also covers significant advances made in the diagnostic and therapeutic approach to both primary tumors and inguinal nodal metastases resulting from penile cancer such as penile sparing surgery and minimally invasive inguinal lymph node surgery. The text will similarly highlights the improvement in cancer specific outcome in the management of loco-regionally advanced (N2/3) penile cancer managed by upfront systemic chemotherapy followed by consolidative surgery in appropriately selected patients based on recent prospective phase II data. It also covers the role of radiotherapy in the management of penile cancer for both primary tumors and/or at sites of regional or distant metastases. Finally, some of the novel systemic approaches being devised in the management of advanced penile cancer along with some upcoming international trials soon to be opened which likely will re-define the present therapeutic approaches to penile cancer are discussed. The Second Edition of Penile Cancer: Diagnosis and Treatment will constitute a comprehensive review of the above mentioned subjects in addition to a few select topics of high clinical relevance, with the readership predominantly consisting of urologists, medical and surgical oncologists, and other healthcare professionals.

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

The aim of the updated book is to include new developments and update the literature in relation to sentinel node biopsy, new radiology techniques and long term epidemiological data. This book is useful for urologists, dermatologists, sexual health physicians as well as those with an interest in virology and genomics related to squamous cell cancers. The surgical techniques are all well illustrated with a step by step guide in order to allow those individuals in centres which are not expert centres to undertake the management of this devastating tumour.

This book provides a comprehensive and state-of the-art approach to caring for penile carcinoma patients and provides foundational information related to the molecular pathways implicated in penile carcinogenesis and progression. Penile carcinoma remains one of the most debilitating and life-altering malignancies to affect men, with significant impacts on quality of life, erectile function/sexual activity, and length of life. This book illuminates recent advances in penile cancer sparing treatment approaches and oncologically appropriate therapeutic options that help to maintain quality of life, sexual function, and intimacy for patients. It also elucidates recent understandings of human papilloma virus (HPV) and non-HPV driven pathways, which are suspected to have distinct treatment responses and prognoses. The book explores the management of inguinal lymph nodes in the setting of penile cancer, which can now be managed with the integration of key surgical principles/techniques including the adoption of minimally invasive surgery. Considering a multidisciplinary treatment approach for patients exhibiting either locally advanced or more widespread metastatic disease, the book introduces novel systemic therapies currently in development. Further, this book raises clinician awareness of the significant psychosocial impact of penile carcinoma on patients and their families. Penile Carcinoma: Therapeutic Principles and Advances provides readers with the necessary knowledge and insight to care for penile cancer patients with the use of truly state-of-the-art diagnostic and therapeutic approaches. Cancer patients and their families will greatly benefit from adoption of these principles and the accessibility of such advances to their personalized care.

Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular pathology and, where applicable, data from clinical trials. The practical treatment guidelines included for each tumor type are written by experts and fully referenced.

This latest book within the Management of Urology series provides a concise and up to date overview of all aspects of penile cancer care. It is an ideal resource for urological trainees and established clinicians seeking an easy-to-digest summary of the topics covered, particularly for those working towards their final specialist examinations. Each chapter covers topics from the aetiology and molecular biology of the disease, diagnostic work up of patients and the differing surgical or non-surgical management techniques available. Learning objectives and key reading sections are included within every chapter that reinforce key points and facilitate the reader in developing a deeper understanding of the topic. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.