Pathology Of Multiple Pregnancy

Pathology of Multiple Pregnancy collates case material from over 500 autopsies (including embryos) and 1200 placentas from twins, triplets, and higher multiples with selected literature on human multiple reproduction. It emphasizes important new concepts of pathophysiology and interpretation of less than ideal outcomes of multiple conception based on over 30 years experience in the field. Aspects of perinatal pathology unique to twins and higher multiples are emphasized, with practical suggestions for the service pathologist, including items of potential medico-legal significance. Controversial topics, such as the value of studies of concordance for diseases or malformations, and the significance of inter-twin anastomoses, are addressed and suggestions made for further investigation. A close working relationship between pathologists and clinical colleagues is encouraged by discussion of clinico-pathological correlations. And, the most recent discussions on mechanisms of twinning and genetic versus environmental influences on the development of twins are presented.

A guide to identifying disease processes in the placenta affecting pregnancy outcome, with current diagnostic criteria and clinical consequences.

This is a unique, much-needed full-color atlas-textbook on twinning and multiple pregnancy. It features nearly 300 beautiful, original color plates, covers in great detail material that has never previously been synthesized into a coherent whole, and is based on the very latest advances in knowledge about the biology and pathology of twins and higher order multiple pregnancies. Special sections deal with the lives of twins and their parents, how to examine twin and HOMP placentas, how to photograph twins for medical purposes, and how to test twin zygosity. The authors are among the world's foremost specialists in the field, widely renowned for their leadership and expertise.

Based on the RCOG Training Module in Fetal Medicine, this book provides a knowledge base for practitioners in obstetrics and maternal-fetal medicine.

The fourth edition of the classic reference in the field of fetal and neonatal pathology, this revised and updated book retains the overall format of previous editions, presenting the same practical approach to the examination of both fetuses and perinatal deaths. It provides essential clinical and pathophysiological information and discusses the pathogenesis of abnormalities as a basis for appropriate methods of investigation. While primarily addressing the morbid anatomist and histopathologist, it is also a valuable resource for obstetricians, neonatologists and paediatricians.

Updated by a team of internationally renowned experts, this book gives a thorough overview of fetal pathophysiology and an evidence base for in utero: both medical (non-invasive) and surgical treatments. Many topics are expanded to cover recent advances, including: stem cell transplantation; tissue scaffolding; minimally invasive approaches to 'open fetal surgery'; the etiology, prevention and treatment of preterm birth and PROM; the genetic etiologies of fetal disease; and gene therapy. In addition, there are in-depth discussions as to the role of open fetal myelomeningocele repair and several fetoscopic approaches to therapy. The international editors have added important new chapters on reducing stillbirth and prenatal counselling. This book is an invaluable reference guide to the latest fetal therapy options, and an essential, in-depth study book for maternal-fetal and neonatology specialists.

This book performs a distinct introduction to the pathology of the placenta and its membranes, abortion material included, with the aim to facilitate and protect the quality of the morphological placental diagnostics by the pathologists. Seven chapters with coloured figures illustrating gross anatomy, development and maturation of the placenta explain the functional morphology in its clinical correlation of single and multiple findings for the pathologists, obstetricians and neonatologists. Moreover, the book contributes to a better understanding of pre- and perinatal investigations, maternal diseases, fetal outcomes and follow up of the newborns, as well as to the prevention of worse outcome in further pregnancies. The atlas intends to stimulate the interest for perinatal pathology and to contribute to a better interdisciplinary understanding of pathologists and clinicians, midwives and nurses.

Practical, evidence-based guide to managing ART pregnancies, based on 30 years of clinical experience, including gynaecological, genetic and obstetric complications.

Establishing the study of multiple pregnancy and the perinatal care of children from multiple births as a recognized specialty within maternal-fetal medicine, the first edition of Multiple Pregnancy was a landmark publication. Fully revised, this new Second Edition has been expanded to include more on epidemiology, biologic mechanisms, the impact of infertility treatments, prenatal diagnosis, and fetal therapy. The book presents all facets of the clinical, psychosocial, and practical issues of multiple gestation and the care of multiplets.

The most comprehensive evidence-based guide to both obstetrics and gynecology Aimed at practicing obstetricians, gynecologists, and trainees in the specialty, Evidence-based Obstetrics and Gynecology concentrates on the clinical practice areas of diagnosis, investigation and management. The first section of the book discusses evidence-based medicine methodology in the context of the two specialties. The second and third sections cover all the major conditions in obstetrics and gynecology, with each chapter reviewing the best available evidence for management of the particular condition. The chapters are structured in line with EBM methodology, meaning the cases generate the relevant clinical questions. Evidence-based Obstetrics and Gynecology provides in-depth chapter coverage of abnormal vaginal bleeding; ectopic pregnancy; pelvic pain; lower genital tract infections; contraception and sterilization; breast diseases; urogynecology; endocrinology and infertility; puberty and precocious puberty; cervical dysplasia and HPV; cervical, vaginal, vulvar, uterine, and ovarian cancer; preconception care; prenatal care and diagnosis; drugs and medications in pregnancy; maternal complications; chronic hypertension; diabetes mellitus; thyroid disease; neurologic disease; psychiatric disease; postterm pregnancy; fetal complications; preeclampsia; and more. First book to address evidence-based practice for obstetrics and gynecology combined EBM is a highly relevant approach for this high risk specialty Edited by leading US specialist involved in the evidence-based medicine movement Evidence-Based Obstetrics and Gynecology is an important text for obstetricians and gynecologists in practice and in training, as well as for specialist nurses.