New Insights Into Behavioral Pharmacology

First published in 1986. This monograph is based on a conference sponsored by the Human Learning and Behavior Branch of the National Institute of Child Health and Human Development, NIH. The meeting that was held at the Xerox Center in Leesburg, Virginia, in August 1983, brought together a group of leading researchers for the purpose of providing an overview of the emerging field of developmental behavioral pharmacology. More specifically, as is evidenced by the chapters in this volume, the intent was to put the field into historical perspective, render a working definition, and outline strategies and tactics for conducting behavioral pharmacological research in the developing organism.

First Published in 1989. Routledge is an imprint of Taylor & Francis, an informa company.

Advances in Behavioral Pharmacology, Volume 4 covers papers about the advances in behavioral pharmacology. The book presents papers on the behavioral mechanisms of drug dependence; the effects of food deprivation on drug-reinforced behavior across most types of drugs abused by humans, routes of self-administration and species; and a biobehavioral approach to treatment of amphetamine addiction. The text also describes the behavioral effects of nicotine in human and infrahuman studies; the behavioral pharmacology of cigarette smoking; the problems and perspectives in the behavioral toxicity of lead; and the use of discriminative behavior as an index of toxicity. Behavioral pharmacologists, psychiatrists, pharmacologists, psychologists, physicians, and students taking these courses will find the book invaluable.

Behavioral Pharmacology of Drug Abuse: Current Status, Volume 93 provides an update on our current understanding of animal and human behavioral pharmacology in major classes of drugs of abuse, including nicotine, alcohol, opioids, psychostimulants, and hallucinogens, drug-environment interactions, neurochemical mechanisms and medications developments. This volume updates the field of behavioral pharmacology based on new knowledge gained in the past decade. Provides accurate and updated reviews from selected experts on covered topics Presents useful graphic material for ease of reading Covers a wide range of topics that are highly integral to offer a panoramic view of the field of behavioral pharmacology

vii Drugs and sex are two topics about which most people have strong opinions and weak understanding. Knowledge of each can be gained in many ways, all with associated rewards and risks. Like all textbooks, this one was written in the belief that reading can foster learning. The book is intended to introduce principles of behavioral pharmacology to readers with little or no knowledge of the discipline but with an interest in how drugs affect human behavior. Gleaning anything of value from the text requires two things from the reader. The first is a willingness to accept an analysis of drug effects that shares little with folklore or common sense no tions of drug action. The second is a willingness to accept the fact that the behavioral effects of drugs are complex and depend upon a sizable number of pharmacological and behavioral variables. Unless one is aware of these factors and how they determine a drug's actions, the behavioral effects of drugs can be neither pre dicted nor meaningfully explained. If it does nothing else, this volume will make it obvious that the behavioral effects of drugs are lawful and can be predicted and understood on the basis of well-established relations between empirical phenomena. De scribing these relations and exploring how they allow behavioral ix x PREFACE pharmacologists to make sense of drug effects that are otherwise incomprehensible was a major goal in preparing the text.

Methods in Behavioral Pharmacology is unique in offering a complete description and critical evaluation of most, if not all, methods available to study the effects of drugs on behavior. It stands apart in that it is not limited to the analysis of a particular class of pharmacological agents in a limited number of paradigms. Methods in Behavioral Pharmacology covers all paradigms without reference to specific pharmacological compounds. The book provides a comprehensive overview of the methodology used to study the behavioral effects of legal and illegal drugs. It also provides an in-depth presentation of dependent variables, their quantification and a critical evaluation of their advantages and disadvantages. An excellent work, contributed to by well-known experts in the different fields of behavioral pharmacology.

There are hundreds, if not thousands, of substances that are used to modify behavior. While different classes of substances have known effects, one has only to see a group of people drinking to excess to recognize that not everyone responds in the same way to a given substance. Why do substances have the behavioral effects they do, and why do individuals vary in their responses to them? This book provides a conceptual framework for answering such questions. Introduction to Behavioral Pharmacology includes a short overview of behavioral analysis and general pharmacology, followed by detailed discussion of assessment of drug effects, the stimulus properties of drugs, drug abuse, and more.

ALERT: Before you purchase, check with your instructor or review your course syllabus to ensure that you select the correct ISBN. Several versions of Pearson's MyLab & Mastering products exist for each title, including customized versions for individual schools, and registrations are not transferable. In addition, you may need a CourseID, provided by your instructor, to register for and use Pearson's MyLab & Mastering products. Packages Access codes for Pearson's MyLab & Mastering products may not be included when purchasing or renting from companies other than Pearson; check with the seller before completing your purchase. Used or rental books If you rent or purchase a used book with an access code, the access code may have been redeemed previously and you may have to purchase a new access code. Access codes Access codes that are purchased from sellers other than Pearson carry a higher risk of being either the wrong ISBN or a previously redeemed code. Check with the seller prior to purchase. -- An up-to-date overview of behavioral pharmacology. Drugs & Behavior starts with descriptions of basic pharmacological concepts of drug administration and pharmacokinetics, research methodology including clinical trials, tolerance and withdrawal, drug conditioning, addiction processes, and the neuroscience of drug action. Each chapter applies these concepts to different classes of recreational and therapeutic drugs. Each chapter also includes a section on the history of the drug class being described to place the drugs in their historical and social context. The text is written to be understandable to students without a background in pharmacology, neuroscience, or psychology. Learning Goals Upon completing this book, readers should be able to: Understand the behaviors of people who use drugs as medicine and for recreation Understand new trends and developments in pharmacology Identify the subjective, behavioral, and neurological differences between the use of both classes of drug Note: MySearchLab does not come automatically packaged with this text. To purchase MySearchLab, please visit: www.mysearchlab.com or you can purchase a ValuePack of the text + MySearchLab (at no additional cost): ValuePack ISBN-10: 0205900909.

The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.