Mup

Two girls wrangle with the themes of growing up and changing while embarking on a rollicking adventure to save the environment. A full color, 280-page graphic novel for children ages 7+. ​

A promising new technology, wireless mesh networks are playing an increasingly important role in the future generations of wireless mobile networks. Characterized by dynamic self-organization, self-configuration, and self-healing to enable quick deployment, easy maintenance, low cost, high scalability, and reliable services, this technology is beco

Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology. Provides an up-to-date review on the practice of neurophysiological techniques in the assessment of neurological disease Explores the electrophysiological techniques used to better understand neurological function and dysfunction, first in the area of consciousness and epilepsy, then in the areas of the peripheral nervous system and sleep Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

The present volume of "Current Topics in Microbiology and Immunology" is a series of papers on subjects that are relevant to the growing use of 'wild mice' in immunological, microbiological and genetical research. 'Wild mice' is a jargonistic term that is used chiefly in the laboratory to refer to the naturally living forms of house mice (Mus musculus) and also other species closely related to M. musculus. This group of species is designated by systematists as the genus Mus. Immunologists began 20 years ago to study the polymorphisms of 1mmunoglobulins and major histocompatibility complex antigens in wild mice. An extrordinary extension of the highly polymorphic array of phenotypes known in inbred mice was encountered. Breeding stocks of wild mice were brought into the laboratory. This included not only M. musculus but a)so many of the available species in the genus Mus-from Southeast Asia ~nd Europe. This availability led to other comparisons of 'wild' and inbred mice and the discovery of other new and interesting phenotypes and genotypes. It became apparent that inbred strains of mice provided only a limited window for viewing the genetic diversity of Mus musculus.

This report describes the partially completed correctness proof of the Viper 'block model'. Viper [7,8,9,11,23] is a microprocessor designed by W. J. Cullyer, C. Pygott and J. Kershaw at the Royal Signals and Radar Establishment in Malvern, England, (henceforth 'RSRE') for use in safety-critical applications such as civil aviation and nuclear power plant control. It is currently finding uses in areas such as the de ployment of weapons from tactical aircraft. To support safety-critical applications, Viper has a particulary simple design about which it is relatively easy to reason using current techniques and models. The designers, who deserve much credit for the promotion of formal methods, intended from the start that Viper be formally verified. Their idea was to model Viper in a sequence of decreasingly abstract levels, each of which concentrated on some aspect ofthe design, such as the flow ofcontrol, the processingofinstructions, and so on. That is, each model would be a specification of the next (less abstract) model, and an implementation of the previous model (if any). The verification effort would then be simplified by being structured according to the sequence of abstraction levels. These models (or levels) of description were characterized by the design team. The first two levels, and part of the third, were written by them in a logical language amenable to reasoning and proof.

Bacteria are among the earliest forms of life on Earth. Notwithstanding their small size and primitive origin, bacteria still have a tremendous impact on everyday human life. Over the centuries, research into bacteria have provided and enriched the fundamental biological knowledge due to their readily measured processes and effects on higher organisms. Although molecular genetics and microbiology were among the scientific fields that have mostly benefited from the discoveries made in bacteria, our current state of knowledge has gone beyond what anyone could have ever imagined. The present Research Topic aims to cover new and exciting broad aspects of the importance of bacteria to human life, both positive and negative influences. Regulation of bacterial gene expression, replication and segregation control mechanisms, cell to cell communication via quorum sensors, and the relatively recent finding of bacterial immunity via CRISPR, have led to the development of many, and very important new tools in biotechnology and the emerging field of molecular medicine. The battle against infectious diseases has also benefited from the genetic approaches that have been developed in the quest for finding new targets and novel drugs against pathogenic bacteria. At the next level, the human microbiome project has opened up new avenues in understanding the role of bacteria in human health and wellbeing. Finally, the relationship between bacterial infections and human cancers will also be covered, a subject that is still under verification through rigorous experimental approaches. Special emphasis will be given to the bacterial accessory genome, i.e the mobilome, as the primary cause of health-threatening antimicrobial resistance and the production of toxins and virulence factors. Taking into account the evolutionary importance of horizontal gene transfer and the additional beneficial roles of certain bacterial mobile genetic elements, they help project best “the Good, the Bad and the Ugly” outline of this topic. At the time this eBook is about to be published, our Research Topic has registered nearly 55, 000 views.

*Offers a comprehensive guide to medical aspects *Covers important classic and newer topics *Presents a practical and manageable level of detail