Intelligent Bioinformatics

Bioinformatics is contributing to some of the most important advances in medicine and biology. At the forefront of this exciting new subject are techniques known as artificial intelligence which are inspired by the way in which nature solves the problems it faces. This book provides a unique insight into the complex problems of bioinformatics and the innovative solutions which make up ‘intelligent bioinformatics’. Intelligent Bioinformatics requires only rudimentary knowledge of biology, bioinformatics or computer science and is aimed at interested readers regardless of discipline. Three introductory chapters on biology, bioinformatics and the complexities of search and optimisation equip the reader with the necessary knowledge to proceed through the remaining eight chapters, each of which is dedicated to an intelligent technique in bioinformatics. The book also contains many links to software and information available on the internet, in academic journals and beyond, making it an indispensable reference for the 'intelligent bioinformatician'. Intelligent Bioinformatics will appeal to all postgraduate students and researchers in bioinformatics and genomics as well as to computer scientists interested in these disciplines, and all natural scientists with large data sets to analyse.

An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters.

This book constitutes the thoroughly refereed post-conference proceedings of the 14th International Meeting on Computational. Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2017, held in Cagliari, Italy, in September 2017. The 19 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medical informatics, computational approaches to life sciences in general.

Artificial Intelligence in Bioinformatics: From Omics Analysis to Deep Learning and Network Mining reviews the main applications of the topic, from omics analysis to deep learning and network mining. The book includes a rigorous introduction on bioinformatics, also reviewing how methods are incorporated in tasks and processes. In addition, it presents methods and theory, including content for emergent fields such as Sentiment Analysis and Network Alignment. Other sections survey how Artificial Intelligence is exploited in bioinformatics applications, including sequence analysis, structure analysis, functional analysis, protein classification, omics analysis, biomarker discovery, integrative bioinformatics, protein interaction analysis, metabolic networks analysis, and much more. Bridges the gap between computer science and bioinformatics, combining an introduction to Artificial Intelligence methods with a systematic review of its applications in the life sciences Brings readers up-to-speed on current trends and methods in a dynamic and growing field Provides academic teachers with a complete resource, covering fundamental concepts as well as applications

This book – in conjunction with the volumes LNCS 8588 and LNAI 8589 – constitutes the refereed proceedings of the 10th International Conference on Intelligent Computing, ICIC 2014, held in Taiyuan, China, in August 2014. The 58 papers of this volume were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections such as machine learning; neural networks; image processing; computational systems biology and medical informatics; biomedical informatics theory and methods; advances on bio-inspired computing; protein and gene bioinformatics: analysis, algorithms, applications.

This book encapsulates and occupies recent advances and state-of-the-art applications of nature-inspired computing (NIC) techniques in the field of bioinformatics and computational biology, which would aid medical sciences in various clinical applications. This edited volume covers fundamental applications, scope, and future perspectives of NIC techniques in bioinformatics including genomic profiling, gene expression data classification, DNA computation, systems and network biology, solving personalized therapy complications, antimicrobial resistance in bacterial pathogens, and computer-aided drug design, discovery, and therapeutics. It also covers the role of NIC techniques in various diseases and disorders, including cancer detection and diagnosis, breast cancer, lung disorder detection, disease biomarkers, and potential therapeutics identifications.

This book constitutes the refereed proceedings of the International Conference on Intelligent Computing, ICIC 2006, held in Kunming, China, in August 2006. The book presents 165 revised full papers, carefully reviewed. Topics covered include ant colony optimization, particle swarm optimization, swarm intelligence, autonomy-oriented computing, quantum and molecular computations, biological and DNA computing, intelligent computing in bioinformatics, intelligent computing in computational biology and drug design, computational genomics and proteomics, and more.