Handbook Of Cardiac Transplantation

Leading physicians summarize in this easy-to-use and eminently practical handbook the day-to-day management of transplant donors and recipients at Columbia-Presbyterian Medical Center. Topics covered range from surgical techniques, pathology, and immunosuppression, to posttransplant management, pediatric heart transplantation, surgical alternatives, and mechanical circulatory assistance as a bridge to transplantation. The authors also discuss congenital transplant techniques, state-of-the-art perioperative management techniques and protocols, and UNOS regulation and nurse coordination.

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​

A heart transplant is a surgical transplantation procedure that is performed on patients suffering from severe coronary artery disease or end-stage heart failure. A functioning heart from a recently deceased organ donor is implanted into a patient when other medical or surgical treatments have failed to suffice. It is not considered a cure but a life-saving treatment that is intended to improve the chances of survival and provide a better quality of life to individuals. Patients who do not qualify for a heart transplant may be prescribed a left ventricular assist device (LVAD) or an artificial heart. In some cases, a heart-lung transplant is performed in patients with diseased heart and lungs. Nearly 3,500 heart transplant surgeries are performed worldwide every year. The survival period post-operation is averaged to be at 15 years. This book presents the complex aspects of heart transplantation in the most comprehensible and easy to understand language. Different approaches, evaluations, methodologies and advanced studies on heart transplantation have been included in this book. It will be a valuable resource for cardiologists, cardiac surgeons, residents and students alike.

Over the past ten years, cardiac transplantation has evolved from an exper imental procedure performed in a handful of university centers to a viable therapeutic modality now performed in more than 150 centers worldwide. The complexity of the procedure, the changing immunosuppressive re gimes, and the follow-up care have necessitated a multidisciplinary ap proach involving a variety of medical, nursing, and social sciences special ties and subspecialties. In addition, health care trainees and referring physicians are increasingly becoming involved in the care of the cardiac transplant recipient. This book does not attempt to be a comprehensive treatise on cardiac transplantation; rather, we hope that it will serve as a manual and guideline for all health professionals involved in cardiac trans plantation. JEFFREY D. HOSENPUD, M.D. Contents Preface v Contributors IX 1. Cardiac Transplantation: An Overview JEFFREY D. HOSENPUD AND ALBERT STARR Immunogenetics and Immunologic Mechanisms of 2. Rejection 15 DOUGLAS J. NORMAN 3. Medical Therapy Tailored for Advanced Heart Failure 33 LYNNE WARNER STEVENSON 4. Ventricular Assistance as a Bridge to Cardiac Transplantation 53 D. GLENN PENNINGTON AND MARC T. SWARTZ Recipient Selection for Cardiac Transplantation 71 5. GEORGE A. PANTELY 6. Donor Selection and Management for Cardiac Transplantation 85 JEFFREY SWANSON AND ADNAN COBANOGLU 7. Operative Techniques and Early Postoperative Care in Cardiac Transplantation 95 ADNAN COBANOGLU Endomyocardial Biopsy: Techniques and Interpretation of 8.

Cardiopulmonary Transplantation and Mechanical Circulatory Support provides a comprehensive review of the field. Written for all tiers of healthcare professionals managing such complex patients. The handbook tackles all topics within this field, including heart failure, heart transplantation, lung transplantation, and all tiers of mechanical circulatory support in adults and paediatric patients. The chapters are written by prominent and globally respected experts in Europe and North America, providing their evidence base as well as personal, practical hints and tips for all practitioners.

It gives us great pleasure to contribute a short introduction outstanding book. This comprehensive work provides an to this important volume. immense fund of information, and will be an invaluable The transplantation of thoracic organs - heart,heart source of knowledge to physicians, surgeons, and scientists lung, lung - is a field of surgery that is expanding annually. for many years to come. The use of mechanical assist devices and artificial hearts to support patients awaiting transplantation is also developing rapidly, and further advances in this field may eventually April 1990 Christiaan Barnard lead to a totally implantable device that will function Cape Town, South Africa successfully for many years. It is therefore timely that such a volume as this should be made available to those who wish to be brought up-to date with the current state of knowledge in these related fields. The editors have done us all a great service in bringing together experts in every aspect of heart and Nazih Zuhdi lung transplantation and replacement to contribute to this Oklahoma City, USA Xl Preface The fields of the transplantation and replacement of thoracic Refinements in bioengineering have enabled mechanical organs have expanded immensely since the first human assist devices and the total artificial heart to support patients to-human heart transplant was performed in 1967. This successfully until a suitable donor becomes available.

This truly comprehensive reference is devoted to every aspect of heart transplantation. It not only covers the surgical procedures for the donor and recipient, but also explores pre and post operative patient management, operative techniques and non-surgical cardiac management options. The 3 reasons you need this book are: (1) Extensive outline and bolded phrases will provide you with QUICK and EASY access to the information; (2) Over 700 illustrations will provide an additional visual aid to enhance your understanding of the text; and (3) Access to information on all the most currently used immunosuppressive drugs and other modalities with helpful tables

This comprehensively covers everything from pathophysiology to the evaluation of patients presenting with heart failure to medical management, device therapy, heart transplantation and mechanical circulatory support, and include relevant cardiac imaging studies such as echocardiograms and magnetic resonance imaging studies which could be seen in their entirety as well as pathology slides, hemodynamic tracings and videos of cardiac surgery such as heart transplants and ventricular assist device implantation. Finally, the book would have videos of patients with heart failure, heart transplants or ventricular assist devices, describing their clinical presentation and experiences. It is structured so that it can be used as a guide by physicians studying for the general Cardiology or Advanced Heart Failure and Cardiac Transplantations Boards.

The Lung Transplantation Handbook (Second Edition), originally published under the title Things You Should Know About Lung Transplantation: Before, During and After has now been updated and expanded in this, the second edition.