Fly

Understanding how a multicellular animal develops from a single cell (the fertilized egg) poses one of the greatest challenges in biology today. Development from egg to adult involves the sequential expression of virtually the whole of an organism's genetic instructions both in the mother as she lays down developmental cues in the egg, and in the embryo itself. Most of our present information on the role of genes in development comes from the invertebrate fruit fly, Drosophila. The two authors of this text (amongst the foremost authorities in the world) follow the developmental process from fertilization through the primitive structural development of the body plan of the fly after cleavage into the differentiation of the variety of tissues, organs and body parts that together define the fly. The developmental processes are fully explained throughout the text in the modern language of molecular biology and genetics. This text represents the vital synthesis of the subject that many have been waiting for and it will enable many specific courses in developmental biology and molecular genetics to focus on it. It will appeali to 2nd and 3rd year students in these disciplines as well as in biochemistry, neurobiology and zoology. It will also have widespread appeal among researchers. Authored by one of the foremost authorities in the world. A unique synthesis of the developmental cycle of Drosophila - our major source of information on the role of genes in development. Designed to provide the basis of new courses in developmental biology and molecular genetics at senior undergraduate level. A lucid explanation in the modern language of the science.

Do Work You Love. Sounds simple, doesn't it? But the reality can be quite different. Whether you're just starting out or simply ready to head in a new direction, you're going to need some help turning your natural skills into success-seeking missiles of radness. On hand is Gavin Strange, a creative working by night under the name of JamFactory and, by day, at Aardman Animations – the Academy Award-winning studio behind Wallace & Gromit and Shaun the Sheep. With advice, encouragement and a reminder that life's too short to not pursue your passion, whatever your age or position – from school leaver or graduate just starting out to CEO ready to head in a new direction, Do Fly will inspire you to: Change your perspective and revamp your mindset Develop creative side projects Stay optimistic and resilient Discover skills and passions you never knew you had! Do Fly is your all-in-one guide, ticket and passport to a new destination. Are you ready for take off?

Fly just wants to have fun flying, but everyone she meets thinks she's doing it all WRONG!

There’s never a dull moment in this funny, beautifully illustrated tale depicting a pesky fly in a whole new light. The housefly in this story doesn’t understand why people won’t share their food with him or play with him . . . and why do they keep trying to give him a swat? He’s not doing any harm! In a clever, interactive novelty book buzzing with fun, Petr Horácek may make readers reluctant to turn the final page.

*"A gentle, effective presentation of grieving and moving on." --Kirkus Reviews (starred review) A beautiful father-daughter story celebrating love, loss, and healing, and one bird's broken wing that may prove impossible to fix. Lucy has always been good at fixing things--the wonky mailbox, broken watches, even Dad's old binoculars. And Lucy is happy to help her dad; they share a special bond. It's just the two of them, after all. So when Lucy finds a tiny bird with a broken wing, she's sure she can fix him too--but not everything that's broken can be fixed. A tender and loving story about loss, healing, and the special connection between fathers and daughters. Praise for When We Fly: "The core of author-illustrator McGeachin’s poignant, fantastical tale is grounded in sobering reality, as Lucy’s father helps her come to terms with the knowledge that not everything is fixable, but he also teaches her that moving forward is possible with the support of loved ones."--Publishers Weekly

“Teague proves that a picture can be worth a thousand words—and almost as many laughs.” —Publishers Weekly (starred review) “Engaging illustrations and the baby bird’s wild ideas will entertain audiences of all ages.” —Booklist (starred review) “Funny, feathery finesse.” —Kirkus Reviews (starred review) Mama bird thinks it’s time for Baby bird’s first flight, but Baby bird has other ideas in this humorous wordless picture book from New York Times bestselling author-illustrator Mark Teague. It’s a big day up in the tree that Mama bird shares with her baby. Mama bird thinks Baby bird is finally ready to leave the nest and learn to fly so he can migrate south with the rest of their flock. But Baby bird isn’t so sure. Can’t his mother keep bringing him worms in their nest? Can’t he migrate in a hot air balloon instead? Or perhaps a car? This silly wordless picture book will keep young readers giggling as Baby bird figures out that he must flap his wings and learn to fly—whether he likes it or not!

Provides step-by-step instructions on tying five hundred trout flies and offers information on tying techniques, tools, and materials.

Pure joy and the power of community radiate from this sweet picture book about a young Black girl’s perseverance and confidence in following her double Dutch dreams. Africa’s grandmother was a double Dutch legend, and Africa knows she can become the same. Her brother scoffs when she signs up for a double Dutch competition, though—how can she hope to compete when she’s never done it before? But Africa has all the tools she needs: memories of her grandmother, her bestie Bianca’s dance moves, her friend Omar’s rhythm, and her classmates’ Mary Mack timing and cartwheels. If Africa can pull everything together to jump some winning moves, she might just fly, but it’s the birthmark in the shape of her name that tells her she’s always been a winner.

Raymond Donne wasn't always a schoolteacher. Not only did he patrol the streets of Williamsburg, Brooklyn, as one of New York's Finest, but being the nephew of the chief of detectives, he was expected to go on to bigger things. At least he was until the accident that destroyed his knees. Unable to do the job the way he wanted, he became a teacher in the same neighborhood, and did everything he could to put the force behind him and come to terms with the change. Then Frankie Rivas, a student in Ray's class and a baseball phenom, stops showing up to school. With Frankie in danger of failing and missing out on a scholarship, Ray goes looking for him, only to find Frankie's father bludgeoned to death in their apartment. Frankie and his younger sister are gone, possibly on the run. But did Frankie really kill his father? Ray can't believe it. But then who did, and where are Frankie and his sister? Ray doesn't know, but if he's going to have any chance of bringing them home safely, he's going to have to return to the life, the people, and the demons he walked out on all those years ago. Intense, authentic, and completely gripping, Tim O'Mara's Sacrifice Fly is an outstanding debut from a stellar new voice in crime fiction.

A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these “first in fly” findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.