Diagnostic Neuropathology Smears

This textbook provides practical information on how to perform and interpret smears and use smears for diagnostic intraoperative neuropathology. The book covers most aspects of brain biopsies that require intraoperative or "frozen section" diagnosis, including tumors, non-neoplastic lesions, infectious diseases, and metastases to the brain. The author also discusses more general aspects of smears, including their preparation and general interpretation. Emphasis is on the structural information about brain lesions supplied by the technique of smears, as well as the patterns of smears produced by different tumors. More than 200 full-color illustrations complement the text.

Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Neuropathology is a visually stunning, easy-to-use reference covering all aspects of neuropathology. Nearly 1,700 outstanding images, including a wide variety of pathology stains and high-quality medical illustrations, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Expert Consult eBook version included, which allows you to search all of the text, figures, and references from the book on a variety of devices. Thoroughly updated content throughout includes new biomarkers and genetic markers; new diagnostic, therapeutic, and prognostic techniques; new entities and antibodies; new immunohistochemical markers; the new "integrated" diagnosis schema; and much more. Features exclusive images not found in the 2016 updated WHO Classification system of CNS neoplasms. Presents complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions. High-quality, carefully annotated color images (both common and rare) depict classic pathological features as well as variant patterns that are prone to creating diagnostic problems. Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index.

Every year dozens of physicians-in-training face, for the first time, the responsibil ity of examining and diagnosing central nervous system tumors or biopsies of the central nervous system, the peripheral nerves or muscles, whose surgical resection has been decided on both as a form of treatment (in the case of tumors) and as means to confirm a presumptive diagnosis. The selection of the most appropriate form of post surgical treatment for most tumors is predicated on the precise identification of the tumor cells. The evaluation of the specimen, by a pathologist, will not only determine whether the lesion is truly neoplastic, but also whether there are histologic indicators of malig nancy. Moreover, in some cases, the pathologist will be asked to determine whether the tumor cells contain certain hormone precursors or receptors, as an example. Recognition of many of the features that one must search for requires the judicious application of methods that may not be readily known to the physicians involved in the various diagnostic procedures. The handling and processing of the tissues as they arrive in the pathology laboratory for the above reasons vary as a function of the organ (or site) of origin of a given tumor as well as a function of the presumptive clinical diagnosis. The material contained in this book series has been organized in an attempt to help the pathologists-in-training, the general pathologists, the neurosurgeons, and neu rologists to understand the logic behind such special requirements.

Practical Surgical Neuropathy-a volume in the new Pattern Recognition series- offers you a practical guide to solving the problems you encounter in the surgical reporting room. Drs. Arie Perry and Daniel J. Brat present diagnoses according to a pattern-based organization that guides you from a histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish illustrations capture key neuropathological patterns for a full range of common and rare conditions, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. No other single source delivers the practical, hands-on information you need to solve even the toughest diagnostic challenges in neuropathology. Includes fully searchable access to the text online at expertconsult.com, along with an image bank of over 1430 downloadable images and tables. Provides all the information essential for completing a sign-out report: clinical findings, pathologic findings, diagnosis, treatment, and prognosis. Illustrates key pathologic and clinical aspects of disease entities through over 1430 superb, high-quality full-color images that help you evaluate and interpret biopsy samples. Presents a team of internationally recognized experts for authoritative and up-to-date information from leading diagnosticians in neuropathology. Features a user-friendly design with patterns color-coded to specific entities in the table of context and text and key points summarized in tables, charts, and graphs so you can quickly and easily find what you are looking for. Directs you to the chapter and specific page number of the in-depth diagnostic guidance you need through a unique, pattern-based visual index at the beginning of the book. Details key diagnostic features associated with rare and esoteric conditions in a visual encyclopedia with distinctive findings and artifacts for unusual patterns at the end of the book. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.

Keeping abreast of the major strides made in the field of neuropathology, Essentials of Diagnostic Surgical Neuropathology brings out its second edition with the aim of keeping the neuroscience community updated with the new developments in neuropathology. This second edition comes close on the heels of the fifth edition of the WHO Classification of Central Nervous System Tumours (WHO CNS5) which was published in 2021. This new edition has retained the concise, point wise format of the earlier edition, making it a handy reference book. While the major changes in this edition are in neoplastic pathology, this book also provides updates in the pathology of non-neoplastic lesions that need surgical intervention. The highlights of the neoplastic section are: Description of new tumour types and subtypes included in the WHO CNS5 Grading of tumours as per WHO CNS5 Relevant immune profile and diagnostic molecular pathology for each tumour according to WHO CNS5. Essential and desirable diagnostic criteria, as defined by WHO CNS5, in a tabular form at the end The salient features of the non-neoplastic section include: New section on Therapy-related Neuropathology Recent classifications of vascular malformations and epilepsy related lesions New section on Infectious and Inflammatory Lesions Mimicking Neoplasms New chapter on Surgical Pathology of Spinal Dysraphism and Other Neural Tube Defects Another important feature includes the addition of a new chapter on techniques viz. Smears in the Rapid Diagnosis of Central Nervous System Lesions Challenges in the Interpretation of Stereotactic Biopsies Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

From the preface: "Pathologists are responsible for the interpretation of tissue samples removed for the purpose of establishing a diagnosis. This textbook has been conceived and arranged in a manner that facilitates the task of arriving at a diagnosis through the evaluation of tissues removed from patients afflicted with neurological complaints. The portion of the diagnostic work-up that is purely "clinical", such as the history of the disease and the results of the physical examination are entirely beyond the scope of this textbook...Extensive descriptions of disease processes, which are available in most of the references cited, have been omitted in favor of relatively detailed descriptions and abundant illustrations of the histologic abnormalities that, as a group, constitute a diagnostic entity."

Oppenheimers Diagnostic Neuropathology, A Practical Manual has become a modern classic in its field, covering the practical aspects of the work of the neuropathologist. Full of sensible advice and observations often omitted from neuropathology texts, it guides the neuropathologist through the methods available to them when facing diagnostic questions. The third edition has been fully updated to ensure authoritative coverage of this complex and fast-moving discipline. The experience of the authors is apparent on every page, where superb illustrations combine with an accessible writing style to present complex, academic information that could otherwise prove formidable to trainees and professionals alike. An essential reference for postgraduate students of neuropathology and histopathology, who need to acquire an understanding of neuropathology as part of their training, this book will also be of interest to trained neuropathologists, neurologists, neurosurgeons and neuroradiologists.

Part of the in-depth and practical Pattern Recognition series, Practical Surgical Neuropathology, 2nd Edition, by Drs. Arie Perry and Daniel J. Brat, helps you arrive at an accurate CNS diagnosis by using a pattern-based approach. Leading diagnosticians in neuropathology guide you from a histological (and/or clinical, radiologic, and molecular) pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Almost 2,000 high-quality illustrations capture key neuropathological patterns for a full range of common and rare conditions, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance. Instructive algorithms provide detailed guidance based on 8 major (scanning magnification) patterns and 20 minor (high magnification) patterns – helping you narrow the range of diagnostic possibilities. A user-friendly design color-codes patterns to specific entities, and key points are summarized in tables, charts, and graphs so you can quickly and easily find what you are looking for. Sweeping content updates keep you at the forefront of recent findings regarding gliomas, embryonal neoplasms, meningiomas, pituitary region and pineal tumors, epilepsy pathology, peripheral nerve sheath tumors, neurodegenerative disorders, tumor predisposition syndromes, and much more. Improved pattern call-outs are now linked directly within the chapter, reinforcing the patterns for more efficient and complete understanding.