Cutaneous Lymphoma An Issue Of Dermatologic Clinics E Book

The Editor of this publication is Dr Elise Olsen, Director of the Duke University Cutaneous Lymphoma Research and Treatment Center and professor of Dermatology and Oncology. In 2014, cutaneous lymphoma (CL) is considered a chronic, non-life threatening disease since the majority of patients are diagnosed at early stage, though progression to later stages does result in death from the disease. This issue covers T-cell and B-cell lymphomas, with content emphasis on Mycoides fungoides and Sezary syndrome, the two most common clinically encountered subtypes of CL. Pharmaceutical treatment of the disease is a part of each article and the issue uses the following Treatment outline: Mechanisms of action - Pharmacokinetics - Typical dosing - Response to therapy - Adverse effects - and Pearls to help management using the agent under discussion. Beyond Dermatologists, specialists who would find the information useful are Cancer specialists, Hematologists/Oncologists, Physician Assistants, Nurse Practitioners, and Pharmacists. Some of the topics, written by the word's top experts in this disease, are: Overview of primary cutaneous lymphomas and the applicable staging and classification; Pathologic diagnosis of cutaneous lymphomas; in the section on Mycosis Fungoides and Sezary Syndrome, the clinician and researcher will find such topics as Skin directed medications; Phototherapy; Systemic retinoids; Interferons; HDAC inhibiotrs, Methotrexate and praletexate, along with other chemotherapeutic agents. Also, Bone marrow transplant; Diagnosis and management of CD30+ Lymphoproliferative disorders; and Diagnosis and management of primary cutaneous B cell lymphomas.

In this issue of Dermatologic Clinics, guest editor Dr. Stan N. Tolkachjov brings his considerable expertise to Cutaneous Oncology Update. Top experts in the field cover key topics such as T-cell lymphomas; B-cell lymphomas; Mohs micrographic surgery; mesenchymal carcinomas; cutaneous oncology in the immunosuppressed; approaches to tumors of the nail unit and genitalia; and more. Contains 16 relevant, practice-oriented topics including squamous cell carcinoma (including high-risk); targeted therapy and immunotherapy in non-melanoma skin cancer; melanoma; targeted therapy and immunotherapy in melanoma; genetic expression profiles in cutaneous oncology; and more. Provides in-depth clinical reviews on cutaneous oncology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Dermatologic Clinics, guest edited by Dr. Lindsay C. Strowd of Wake Forest Baptist Health, is devoted to the Intersection of Dermatology and Oncology. This issue focuses on Melanoma, Nonmelanoma Skin Cancer, Cutaneous Lymphoma, Other Cutaneous Malignancies, Special Topics in Skin Cancer Diagnosis and Treatment, Dermatology in the Diagnosis of Non-cutaneous Malignancy, Dermatology in the Management of Non-cutaneous Malignancy, and Genodermatoses with Neoplastic Behavior. Articles in this issue include: Update on current treatment recommendations for primary cutaneous melanoma; Nonsurgical treatments for advanced melanoma; Update on current treatment recommendations for NMSC; Nonsurgical treatments for NMSC; Diagnosis and management of CBCL; Diagnosis and management of CTCL; Lymphomatoid papulosis and other lymphoma-like diseases (PLC, PLEVA, CD30+ disease); Dermatofibrosarcoma protuberans updates; Merkel cell carcinoma updates; Kaposi sarcoma updates; Skin cancer in skin of color patients; Skin cancer detection technology; Paraneoplastic diseases; Cutaneous metastases of internal tumors; Cutaneous side effects of chemotherapy agents; GVHD treatment updates; Phakomatoses (NF, TS); and Hereditary tumor syndromes with skin involvement (Gorlins, Lynch, XP, etc.).

Knowledge of cutaneous lymphomas has been growing significantly as a result of important discoveries in immunology, molecular biology, and immunohistochemistry. Improved clinical pathologic correlation and follow-up data, as well as the synergistic collaboration among different lymphoma registries and specialists from several academic medical centers have greatly contributed to the understanding of the difficult field of cutaneous lymphoproliferative disorders. While these advances have increased understanding of skin lymphomas, they have also produced an extensive and sometimes confusing litany of articles, studies, and classification schemes. This issue on Cutaneous Lymphomas in Surgical Pathology Clinics provides an organized and updated review of this challenging topic by leading experts. It bridges critical knowledge gaps in the diagnosis of cutaneous lymphomas. Sezary Syndrome, Mycosis Fungoides and variants are presented along with B-cell, CD30, lymphoproliferative disorders among others. In addition to multiple clinical and microscopic images, tables and algorithms are presented to aid in diagnosis and staging. Beyond its usefulness to general pathologists, dermatopathologists, and hematopathologists, this information is intended to be helpful for dermatologists, hematologists/oncologists, fellows, and residents.

In this issue of Medical Clinics, Guest Editor Jeffrey Callen brings his considerable expertise to the topic of Dermatology. Top experts in the field cover key topics such as alopecia, psoriasis, Cutaneous manifestations of diabetes, Diagnosis and management of cellulitis, and more. Provides in-depth, clinical reviews in Dermatology, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains more than 10 relevant, practice-oriented topics including Recognition and management of Severe Cutaneous Adverse Drug Reactions (including DRESS, SJS and TEN); Diagnosis and management of eczemas including atopic, hand dermatitis and contact dermatitis; Recognition, staging and management of melanoma; Diagnosis and management of leg ulcers; Approach to the patient with pruritus; and more.

This issue of Dermatologic Clinics, guest edited by Elizabeth A. Buzney, MD, is devoted to Phototherapy. Articles in this important issue include: Nuts and Bolts: Optimizing Narrowband UVB Phototherapy Regimens for Psoriasis; The (Lost) Art of Managing PUVA Phototherapy; Distinguishing Myth from Fact: Photocarcinogenesis and Phototherapy; How Does It Work: The Immunology underlying Phototherapy; Phototherapy for Vitiligo; Phototherapy in Skin of Color; Phototesting Protocols and Interpretation and Managing Photodermatoses with Phototherapy; Utilizing UVA-1 Phototherapy; Using Phototherapy in the Pediatric Population; Home Phototherapy; Phototherapy for Cutaneous T-Cell Lymphoma; Creating and Managing a Phototherapy Center; Phototherapy for Itch; Beyond the Booth: Excimer Laser for Cutaneous Conditions; and Feeling the Burn: Phototoxicity and Photoallergy.

In this issue of Dermatologic Clinics, guest editor Dr. Susan C. Taylor brings her considerable expertise to the topic of Diagnosing Skin Disease in Skin of Color. Top experts in the field cover key topics such as hidradenitis suppurativa; psoriasis; atopic dermatitis; diagnosing disorders of facial erythema; disorders of facial hyperpigmentation; disorders of hypopigmentation and depigmentation; and more. Contains 14 relevant, practice-oriented topics including scarring alopecia; scalp infections and inflammation; collagen vascular disease; cosmetic enhancement pitfalls; sarcoidosis; skin cancer in skin of color; disorders of children; and more. Provides in-depth clinical reviews on diagnosing skin disease in skin of color, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.