Current Topics In Heart Failure

Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.

The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

In order to provide the latest and most sophisticated treatment, cardiology physicians must possess current knowledge of a vast amount of translational research in the pathophysiology of structural heart disease and its associated disorders as well as recent advances in diagnostic techniques and pharacogenic and interventional therapies. Topics in Structural Heart Disease provides expert reviews and assessment of the most recent clinical research and on current trends in evaluation, diagnosis, and clinical management. Reviews include assessment of emerging data and indications of likely key advances with significant impact on clinical practice in the near future. This volume is a must-have for every cardiologist needing to be fully current on recent advances in structural heart disease and its associated disorders. About the Series Developed by expert faculty at the Cornell Division of Cardiology, the Emerging Concepts in Cardiology series edited by Craig T. Basson and Bruce B. Lerman, provides "state of the art" reviews of each topic from a clinical perspective, with expert analysis of current clinical research and emerging basic and traditional research issues all in concise, attractive and well-illustrated texts.

In order to provide the latest and most sophisticated treatment the cardiology clinician must have current knowledge of a vast amount of translational research in the pathophysiology of these disorders as well as be aware of recent advances and issues in pharmacogenic and interventional therapies. Topics in Arrhythmias and Ischemic Heart Disease provides expert reviews and assessment of the most recent clinical research and on current trends in evaluation, diagnosis, and clinical management. Reviews include assessment of emerging data and indications of likely key advances with signifiacnt impact on clinical research in the near future. This volume is a must-have for every cardiologist needing to be fully current on recent advances in ischemic heart disease and arrhythmic disorders. About the Series Developed by expert faculty at the Cornell Division of Cardiology, the Emerging Concepts in Cardiology series edited by Craig T. Basson and Bruce B. Lerman, provides "state of the art reviews" of each topic from a clinical perspective, with expert perspectives in current clinical research and emerging basic and traditional research issues all in a concise, attractive and well-illustrated texts.

This issue of Heart Failure Clinics, edited by Drs. Ragavendra R. Baliga and Umesh C. Samal, will focus on Recent Advances in Management of Heart Failure. Topics include, but are not limited to, Neprilysin Inhibition on Systolic HF, If Channel Inhibitor Ivabradine in Heart Failure, Growth Hormone Therapy in Heart Failure, Ultrafiltration in Heart Failure, Aldosterone Receptor Blockade in Diastolic HF, Intravenous Iron Therapy in HF, Management of Secondary Pulmonary Hypertension, Management of Chemotherapy Induced Cardiomyopathy, Management of HF in Adult Congenital Heart Disease, LVADS in Heart Failure, Short Term Circulatory & Right Ventricle support in Cardiogenic Shock, Mitral Valve Repair in HF, Total Artificial Heart, Current Status of Inotropes in Heart Failure, Palliative Therapy in Heart Failure, Subcutaneous ICDs and Leadless Pacemakers, Interventional Heart Failure and Hemodynamic Monitoring, and Management of Sleep Apnea in Heart Failure.

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.