Constructing A Nervous System

A NEW YORK TIMES BEST BOOK OF THE YEAR • From "one of our most nuanced thinkers on the intersections of race, class, and feminism" (Cathy Park Hong, New York Times bestselling author of Minor Feelings) comes a memoir "as electric as the title suggests" (Maggie Nelson, author of On Freedom). A BEST BOOK OF THE YEAR: The New York Times, TIME Magazine, Oprah Daily, The New Yorker, Washington Post, Vulture, Buzzfeed, Publishers Weekly The Pulitzer Prize-winning critic and memoirist Margo Jefferson has lived in the thrall of a cast of others—her parents and maternal grandmother, jazz luminaries, writers, artists, athletes, and stars. These are the figures who thrill and trouble her, and who have made up her sense of self as a person and as a writer. In her much-anticipated follow-up to Negroland, Jefferson brings these figures to life in a memoir of stunning originality, a performance of the elements that comprise and occupy the mind of one of our foremost critics. In Constructing a Nervous System, Jefferson shatters her self into pieces and recombines them into a new and vital apparatus on the page, fusing the criticism that she is known for, fragments of the family members she grieves for, and signal moments from her life, as well as the words of those who have peopled her past and accompanied her in her solitude, dramatized here like never before. Bing Crosby and Ike Turner are among the author’s alter egos. The sounds of a jazz LP emerge as the intimate and instructive sounds of a parent’s voice. W. E. B. Du Bois and George Eliot meet illicitly. The muscles and movements of a ballerina are spliced with those of an Olympic runner, becoming a template for what a black female body can be. The result is a wildly innovative work of depth and stirring beauty. It is defined by fractures and dissonance, longing and ecstasy, and a persistent searching. Jefferson interrogates her own self as well as the act of writing memoir, and probes the fissures at the center of American cultural life.

A NEW YORKER BEST BOOK OF THE YEAR • From "one of our most nuanced thinkers on the intersections of race, class, and feminism (Cathy Park Hong, New York Times bestselling author of Minor Feelings) comes a memoir "as electric as the title suggests" (Maggie Nelson, author of On Freedom). The Pulitzer Prize-winning critic and memoirist Margo Jefferson has lived in the thrall of a cast of others—her parents and maternal grandmother, jazz luminaries, writers, artists, athletes, and stars. These are the figures who thrill and trouble her, and who have made up her sense of self as a person and as a writer. In her much-anticipated follow-up to Negroland, Jefferson brings these figures to life in a memoir of stunning originality, a performance of the elements that comprise and occupy the mind of one of our foremost critics. In Constructing a Nervous System, Jefferson shatters her self into pieces and recombines them into a new and vital apparatus on the page, fusing the criticism that she is known for, fragments of the family members she grieves for, and signal moments from her life, as well as the words of those who have peopled her past and accompanied her in her solitude, dramatized here like never before. Bing Crosby and Ike Turner are among the author’s alter egos. The sounds of a jazz LP emerge as the intimate and instructive sounds of a parent’s voice. W. E. B. Du Bois and George Eliot meet illicitly. The muscles and movements of a ballerina are spliced with those of an Olympic runner, becoming a template for what a black female body can be. The result is a wildly innovative work of depth and stirring beauty. It is defined by fractures and dissonance, longing and ecstasy, and a persistent searching. Jefferson interrogates her own self as well as the act of writing memoir, and probes the fissures at the center of American cultural life.

The nervous system is made up of the brain, the nerves, and the spinal cord. But what does the nervous system do? And how do its parts work together to help your body function? Explore the nervous system in this engaging and informative book.

The Human Nervous System is a definitive account of human neuroanatomy, with a comprehensive coverage of the brain, spinal cord, and peripheral nervous system. The cytoarchitecture, chemoarchitecture, connectivity, and major functions of neuronal structures are examined by acknowledged authorities in the field, such as: Alheid, Amaral, Armstrong, Beitz, Burke, de Olmos, Difiglia, Garey, Gerrits, Gibbins, Holstege, Kaas, Martin, McKinley, Norgren, Ohye, Paxinos, Pearson, Pioro, Price, Saper, Sasaki, Schoenen, Tadork, Voogd, Webster, Zilles, and their associates. Large, clearly designed 8-1/2" x 11" format 35 information-packed chapters 500 photomicrographs and diagrams 6,200 bibliographic entries Table of contents for every chapter Exceptionally cross-referenced Detailed subject index Substantial original research work Mini atlases of some brain regions

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. Updates information including all the new developments made in the field since the first edition Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated

In this work, the authors integrate three major basic themes of neuroscience to serve as an introduction and review of the subject.

The decade since the publication of David Butler's Mobilisation of the Nervous System has seen the rapid growth and influence of the powerful and linked forces of the neurobiological revolution, the evidence based movements, restless patients and clinicians. The Sensitive Nervous System calls for skilled combined physical and educational contributions to the management of acute and chronic pain states. It offers a "big picture" approach using best evidence from basic sciences and outcomes data, with plenty of space for individual clinical expertise and wisdom.

The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System, Second Edition, summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This new edition features new chapters on Pain and Addiction to highlight the growing opioid crisis and the ethical issue of prescriptions drug abuse. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. Each chapter includes suggested further readings and/or journal club recommendations. 2016 PROSE Award winner of the Best Textbook Award in Biological and Life Sciences Provides a focused tutorial introduction to the core diseases of the nervous system Includes comprehensive introductions to Stroke, Epilepsy, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system Covers more than 40 diseases from the foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience New Edition features two new chapters on Pain and Addiction