Clinical Neurocardiology

This valuable reference provides a wide range of practical, clinical information for physicians who care for patients with neurological and cardiac problems. Clinical Neurocardiology considers neurological complications arising from cardiac surgery and other cardiac interventions describes neurological findings in heart dise

The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodeling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.

New ideas about intrinsic and extrinsic cardiac intrathoracic neurons, the role of spinal cord and medullary and higher center neurons are presented. The final chapters focus on the role that autonomic neurons play in the maintenance of cardiac function in the conscious state as well as in two major clinical conditions, dysrythimias and heart failure.

Novel concepts about how neurons, from the level of the heart to the sensorium, exert dynamic control over cardiac electrical & mechanical events, are presented in this volume. A focus is on how various components of neural control of the heart remodel during the evolution of cardiac pathologies.

This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.

Combining the research and study of integrative Chinese and Western Medicine, Integrative Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners. This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research. Integrates Western and Chinese medicine for a realistic scope of cardiology treatment Establishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology "Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical use Offers a reference section that lists the latest in published studies Presents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents

The past decade has witnessed dramatic changes in the overlapping space between cardiovascular care and brain health and science. Treatment of high blood pressure has been demonstrated to reduce cognitive impairment and dementia. Subclinical cardiac disorders, including atrial fibrillation, atrial cardiopathy, and patent foramen ovale, are increasingly recognized as modifiable risk factors and causes of stroke; related treatments, such as left atrial exclusion and PFO closure, have become standard of care. Techniques developed originally in the treatment of acute myocardial infarction 30 or more years ago have now become evidence-based standard of care for patients with acute ischemic stroke. Neurocardiology: The Emerging Field of Brain/Heart Interactions addresses important questions and directions for research that lie at the intersection of cardiovascular care and brain science, and provides clinicians with guidance for the care of patients with neurological and cardiovascular disorders, including stroke, dementia, and management of cardiac causes of these conditions.

Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come. Key Features The first comprehensive reference on the emerging field of Neuromodulation Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise Over 1200 pages in splendid full color, richly illustrated Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces

This book describes the varying clinical manifestations of postural tachycardia syndrome (PoTS) and provides a robust yet practical set of clinical tools for those managing patients suffering with this syndrome. Guidance is provided by a range of disciplines relevant to PoTS including general and specialist assessments, associated conditions, diagnostic considerations, therapy and service models. Postural Tachycardia Syndrome: A Concise and Practical Guide to Management and Associated Conditions presents the scientific background and practical information for the busy medical professional, illustrating key features with care-based materials to help them manage this condition, which can be a challenge for patients and clinicians alike.