Cell Movement And Cell Behaviour

Some years ago a book reviewer, perhaps with Freudian honesty, remarked that the book in question 'filled a much needed gap in the literature'. That phrase has haunted the writing of this gap-filler and this preface may be considered an apologia. For a number of years I have found myself teaching various groups of students about cell locomotion and cell behaviour: sometimes science students specializing in cell or molecular biology, sometimes immunologists or pathologists who only wanted a broad background introduction. Those students who were enthusiastic, or who wished to appear so, asked for a general background text (to explain my lectures perhaps), and that is what I hope this book will provide. With luck, other scientists who have only a peripheral interest in cell movement will also find this a useful overview. The more proximate origin of the book was a special 'option' subject which I taught for two years to our Senior Honours Cell Biology students in Glasgow.

This book describes the latest molecular and genetic advances in the study of one of the most fundamental, and yet least understood, processes of life: the movement of cells. Cell locomotion lies at the basis of embryological development, wound healing, and the spread of cancers. The recent advances in identifying the molecular components of cell motility can be found in many publications, but this text uniquely provides a synthesis of the molecular and phenomenological aspects that will be required for an understanding of the controlling processes that underlie cell behavior. The book will benefit final-year students studying molecular/cell biology but it is primarily aimed at graduate research workers, in all biomolecular sciences, who need to understand the wider implications of their research. Besides cell and molecular biologists, these will include workers in oncology, vascular biology, tissue repair, and cell engineering.

This book contains a collection of original research articles and review articles that describe novel mathematical modeling techniques and the application of those techniques to models of cell motility in a variety of contexts. The aim is to highlight some of the recent mathematical work geared at understanding the coordination of intracellular processes involved in the movement of cells. This collection will benefit researchers interested in cell motility as well graduate students taking a topics course in this area.

This book, first published in 1990, provides an overview of the events and mechanisms of morphogenesis.

This book vividly describes how complex and integrated movements can arise from the properties and behaviors of biological molecules. It provides a uniquely integrated account in which the latest findings from biophysics and molecular biology are put into the context of living cells. This second edition is updated throughout with recent advances in the field and has a completely revised and redrawn art program. The text is suitable for advanced undergraduates, graduate students, and for professionals wishing for an overview of this field.

This book surveys the most recent advances in physics-inspired cell movement models. This synergetic, cross-disciplinary effort to increase the fidelity of computational algorithms will lead to a better understanding of the complex biomechanics of cell movement, and stimulate progress in research on related active matter systems, from suspensions of bacteria and synthetic swimmers to cell tissues and cytoskeleton.Cell motility and collective motion are among the most important themes in biology and statistical physics of out-of-equilibrium systems, and crucial for morphogenesis, wound healing, and immune response in eukaryotic organisms. It is also relevant for the development of effective treatment strategies for diseases such as cancer, and for the design of bioactive surfaces for cell sorting and manipulation. Substrate-based cell motility is, however, a very complex process as regulatory pathways and physical force generation mechanisms are intertwined. To understand the interplay between adhesion, force generation and motility, an abundance of computational models have been proposed in recent years, from finite element to immerse interface methods and phase field approaches.This book is primarily written for physicists, mathematical biologists and biomedical engineers working in this rapidly expanding field, and can serve as supplementary reading for advanced graduate courses in biophysics and mathematical biology. The e-book incorporates experimental and computer animations illustrating various aspects of cell movement./div

An interdisciplinary study explaining the dynamics underlying biological motion – one of the most obvious expressions of self-organization. Designed for a broad audience from bioscientists to applied mathematicians, this book considers possible synergetic mechanisms of interaction and cooperation on different microscopic levels.