Cardiopulmonary Transplantation And Mechanical Circulatory Support

Cardiopulmonary Transplantation and Mechanical Circulatory Support provides a comprehensive review of the field. Written for all tiers of healthcare professionals managing such complex patients. The handbook tackles all topics within this field, including heart failure, heart transplantation, lung transplantation, and all tiers of mechanical circulatory support in adults and paediatric patients. The chapters are written by prominent and globally respected experts in Europe and North America, providing their evidence base as well as personal, practical hints and tips for all practitioners.

Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease Comprehensive textbook covering all aspects of the care of patients with advanced heart or lung disease Transplantation and Mechanical Support for End-Stage Heart and Lung Disease is the most comprehensive and contemporary textbook available that addresses the medical and surgical treatment options for patients with end-stage heart and lung disease. All facets of these complex and resource-intensive therapies are covered by leading experts — including the basics of transplant immunology, databases, regulatory and ethical aspects of transplantation and conventional and new modalities of donor organ harvest. Transplantation and Mechanical Support for End-Stage Heart and Lung Disease includes further information on topics such as: Historical developments that facilitated heart and lung transplantation; engineering advances in continuous flow technologies Transplant organizations, oversight, structure, process, databases and registries in the thoracic transplants and MCS field Current strategies in immune modulation, desensitization protocols and mechanisms of allograft rejection and tolerance/immunosenescence Detailed descriptions of donor and recipient surgical procedures as well as comprehensive implantation techniques for all available short- and long-term mechanical circulatory support devices, including ECMO Organ allocation and prioritization, donor evaluation, high risk donors, marginal donors, and risk assessment Richly enhanced with summary tables and color illustrations to provide an engaging and supportive learning experience, the book will serve as a highly valuable source of contemporary knowledge for medical students, residents, nurses, perfusionists, physicians and surgeons involved in the care of these desperately ill group of patients. “This comprehensive book covers all aspects of advanced heart and lung failure treatment, including shock, short-term and durable mechanical assistance, as well as transplantation. The in-depth information will be welcome by newcomers in the field as well as seasoned veterans.” —Andreas Zuckermann, M.D Vice-Chair, Department of Cardiac Surgery, Director of Cardiac Transplantation Program, Medical University of Vienna, Vienna General Hospital “This comprehensive tour-de-force compendium covers practical issues of clinical administration, program development, care pathways, ongoing challenges and opportunities in each treatment area as a must go-to reference for guidance in the rapidly evolving fields of mechanical circulatory support and transplantation.” —Mandeep R. Mehra, MBBS, MSc, FRCP Executive Director, Center for Advanced Heart Disease, Brigham and Women’s Hospital, Harvard Medical School “This unique textbook authored by key opinion leaders is a refreshing ???wind of change??? in our field, one that will well serve all professionals involved in the care of end-stage heart and lung patients for many years to come.” —Marcelo Cypel MD, MSc, FACS, FRCSC Surgical Director Ajmera Transplant Centre at UHN , University of Toronto

This book is a detailed practical guide to the use of ventricular assist devices and total artificial hearts to provide mechanical circulatory support (MCS) in patients with end-stage heart failure. It explains why MCS may be indicated, which patients require MCS, when and how to implant ventricular assist devices or a total artificial heart, and how to avoid potential complications of MCS. Management throughout the period of care is described, from preimplantation to follow-up, and both typical and atypical cases are discussed. The text features numerous helpful tips and tricks relating to surgical and nonsurgical management and is supported by a wealth of high-quality illustrations that document the preoperative evaluation and implantation techniques. Heart transplantation remains the gold standard for the treatment of patients suffering from end-stage heart failure, but the shortage of donors has led to an increase in the use of MCS. This book will assist all physicians, and especially cardiologists and anesthesiologists, who are involved in the care of these patients.

This engaging book provides a state-of-the-art introduction to the rapidly evolving field of mechanical circulatory support therapy in the care of patients with advanced heart failure. It is aimed at healthcare teams around the world who are involved in patient care, research, and teaching of advanced heart failure; healthcare professionals in training; and interested lay persons.In particular, this book• serves as a comprehensive resource and practice guide on all aspects of mechanical circulatory support therapy, starting with an overview on heart failure management and then continuing with the referral and evaluation, the care before and after mechanical circulatory support implantation, the analysis of outcomes and complications, as well as a description of research and societal perspectives in the field of mechanical circulatory support therapy;• is founded on the expertise of Columbia University Medical Center (New York City), which has one of the most renowned heart failure, mechanical circulatory support, and heart transplantation programs in the world;• takes a multidisciplinary integrated healthcare team approach, including the perspectives of cardiologists, cardiac surgeons, nurses, coordinators, social workers, psychologists, physical therapists, financial experts, and bioethicists; and• provides in a unique way the complementary viewpoints from the expert healthcare team's as well as the patient's and family's perspectives, with patient vignettes interspersed throughout the entire text./a

Mechanical Circulatory Support: Principles and Applications offers innovative approaches to complex clinical scenarios and represents the current state-of-the-art for managing patients on mechanical circulatory support devices. Topics are presented in a concise fashion, making it a practical resource for care givers who need a user's manual in the heat of the moment during patient care as well as a reference for a better understanding of the unique components of every device available for human use. This book provides a comprehensive, up-to-date analysis of the most relevant issues facing health care providers in the management of advanced heart failure. With content that features patient selection strategies, implantation techniques, device specific considerations, and management of clinical challenges in the post-operative setting, this textbook offers evidence-based answers to the complex questions facing nurses, perfusionists, advanced practice providers, and physicians.

Mechanical Circulatory Support: Principles and Applications offers innovative approaches to complex clinical scenarios and represents the current state-of-the-art for managing patients on mechanical circulatory support devices. Topics are presented in a concise fashion, making it a practical resource for care givers who need a user's manual in the heat of the moment during patient care as well as a reference for a better understanding of the unique components of every device available for human use. This book provides a comprehensive, up-to-date analysis of the most relevant issues facing health care providers in the management of advanced heart failure. With content that features patient selection strategies, implantation techniques, device specific considerations, and management of clinical challenges in the post-operative setting, this textbook offers evidence-based answers to the complex questions facing nurses, perfusionists, advanced practice providers, and physicians.

An all-in-one guide to mechanical assist devices for the treatment of heart failure This complete guide addresses all of the clinical scenarios encountered by the health care team during the pre-operative, intra-operative, and post-operative periods following device implantation. In addition, it outlines the specific attributes of various technologies that are currently utilized by clinicians, giving you a practical view of how the latest devices work. You’ll also find a mini-catalog of the spectrum of current devices, complete with their technical and clinical specifications. Drawing on the latest published data and the combined global expertise of a renowned author team, Mechanical Circulatory Support puts the field’s most essential perspectives right at your fingertips. FEATURES: The unmatched mechanical circulatory device sourcebook, covering the physiological, technical, regulatory, and clinical aspects of ventricular assist devices Full-color presentation features a wide range of photographs, radiographs, tables, and clearly labeled clinical and schematic illustrations Essential insights into the physiology of heart failure, which provides a basic foundation of knowledge for understanding the role of mechanical circulatory assistance in the management of heart failure Logical two-part organization consisting of: Clinical Considerations in mechanical circulatory support, including device history/development and indications for device therapy; perioperative management; complications; and special considerations (use in infants/children, pulmonary hypertension during LVAD support, and more) Device-Specific Considerations, which provides a mini-catalog of manufacturer’s devices—-from short-term devices to long-term continuous flow devices—-and highlights technical and clinical specifications for each product Guide to appropriate device selection using a simplified framework in an industry that produces an increasing array of short- and long-term therapies Helpful chapter introductions provide essential background information that places each chapter topic in its proper clinical and technical context Conclusions at the end of each chapter offer a concise summary of chapter material Full chapter-ending references provide opportunities for further research

This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.​

After decades of laboratory investigations mechanical circulatory support for the failing heart has entered the clinical arena. Today, a growing number of patients with progressive myocardial failure awaiting cardiac transplantation is successfully bridged to transplantation with ventricular assist devices. The proceedings of the "Mechanical Circulatory Support"-meeting, held in Berlin, October 21-22, 1995, present new aspects of mechanical circulatory support, recent experience with MCS in newborns and children using specially developed small devices, and the results of long-term mechanical assistance. The ability of the myocardium to recover under pressure de-loading and reduced workload is discussed. All these topics open up new perspectives for the use of mechanical circulatory support, not only as a bridge to transplantation, but also as a definitive approach for treating patients with end-stage heart failure. Some of these concepts may even provide real alternatives to heart transplantation, these being sorely needed in light of the severe donor organ shortage. Regulatory as well as ethical aspects of the extended use of mechanical circulatory support systems and new technical developments in the field are discussed by internationally distinguished experts.

This book is a concise, portable handbook that focuses on the clinical use of mechanical blood pumps. All aspects of mechanical circulatory support are addressed, including patient selection, preoperative preparation, operative management, anesthetic considerations and conduct of cardiopulmonary bypass, postop management including complications associated with blood pump use and long-term care and rehabilitation.