Breakthrough

Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

A new shared world anthology featuring a who's who of science fiction writers including Larry Niven, Steven Perry and Gary Gygax. Pledged to stop the predator Khalians, the Fleet must win a decisive victory to break the war's deadlock--and bring peace to their worlds.

Breakthrough: Trusting God for Big Change in Your Church encourages leaders of churches that are struggling and wondering if it's time to close the doors on God's work through them, their family, their church, or their ministry. This book is especially for those who have the audacity to dare to imagine where a new window might open as an old door is closing. Breakthrough reveals gritty, well-grounded hope around every corner.

"Deep in the Caribbean ocean, a nuclear submarine is forced to suddenly abort its mission under mysterious circumstances. Strange facts begin to emerge that lead naval investigator John Clay to a small group of marine biologists who are quietly on the verge of making history. Alison Shaw and her team are preparing to translate the first two-way conversation with another animal species, but they are about to discover much more than they ever expected. When a mysterious object is found on the ocean floor and an unknown group suddenly becomes interested in her work, Alison learns that Clay may be the only person she can really trust. Together they find themselves embroiled in a desperate attempt to stop a catastrophe that spans the Atlantic Ocean and reaches all the way to Antarctica"--Back cover.

People don’t want to just walk through life but seek to walk into it. Life is far from perfect. Often, it’s full of hard choices. Waking up from a coma to discover his eighteen-year-old body contained seven stage-four cancerous tumors, Christopher Stewart’s battle for his life began. For Chris, the easy choice was to fight for his life. The hard one was choosing to be himself in the process. Through this journey, Chris saw firsthand that life is filled with challenge, fear, pain, and chaos but that there is also love and beauty to be found and good memories to be made. Breakthrough offers insight into how beautifully haunting our lives can be, as Chris tells how to: - let go of the expectations to be a pretender - every day choose to be yourself—the person you were destined to be - accept yourself for who you are - chase your dreams, because anything is obtainable! Chris was able to make a breakthrough. And through this book he believes that you can breakthrough too. By facing fear, chaos, and pain, you too can find a more meaningful life.

"Hang on and watch your life take flight with FlyGirl!" -Marcia Wieder, CEO and Founder of Dream University Before she was thirty years old, Vernice "FlyGirl" Armour had become a decorated naval aviator, Camp Pendleton's 2001 Female Athlete of the Year and Strongest Warrior winner, the first female African-American on Nashville's motorcycle police squad, and a member of the San Diego Sunfire professional women's football team. She's a force to be reckoned with, and she believes that women and men from all walks of life have the potential to achieve the highest levels of success with the right flight plan. In Zero to Breakthrough, Vernice turns aspiration into action by revealing how to create the path that will get you out of your rut on onto the runway - cleared for take off. Armour firmly believes that there is no such thing as a dream out of reach. Integrating the foundational concepts of a Breakthrough MentalityTM like preparation, strategy, courage, legacy, and the importance of high spirits and enthusiasm, Zero to Breakthrough helps readers build a sustainable inner force and conviction that result in accomplishing significant goals and becoming an extraordinary member of any business or community. Packed with hard-hitting advice and amazing anecdotes from her adventures on the battlefield and in business, you'll learn strategies like how to: *Stop procrastinating and prepare to lay the groundwork for success *Execute situations with self-discipline to achieve mastery *Acknowledge and move past obstacles & challenges *Feel fear and use it to keep charging, and much more Whether you want to jump up the corporate ladder, start your own business, or develop a passion into a livelihood, Zero to Breakthrough will get you there. For anyone seeking a more fulfilling life, Armour has the ultimate launch pad.

Break through to your peak performance! Whether you're navigating your way on a new team, expanding your leadership role, or just trying to get heard in a meeting, you're facing the kind of workplace challenge we all run into sooner or later: you need a new performance. In Performance Breakthrough, Cathy Salit presents the revolutionary strategies that she's proven successful through over twenty years' experience custom-creating workshops for powerhouse clients including American Express, Nike, Coca-Cola, and DIRECTV. Artfully blending techniques from theatrical performance with the new science of performative psychology, Salit guides readers through forging new relationships guaranteed to yield greater success and satisfaction. Performance Breakthrough outlines proven techniques, including taking an emotional inventory; crafting new scripts for greater confidence, stronger relationships, and better outcomes; building ensembles; improvising; and listening -- really listening -- including accepting others' criticism and input. No matter what your challenge, Salit's innovative philosophy, case studies, practical exercises, and inspiring advice will help you deliver your own top performance.

Exploring some of the ways in which repair practices and perceptions of brokenness vary culturally, Repair, Brokenness, Breakthrough argues that repair is both a process and also a consequence which is sought out—an attempt to extend the life of things as well as an answer to failures, gaps, wrongdoings, and leftovers. This volume develops an open-ended combination of empirical and theoretical questions including: What does it mean to claim that something is broken? At what point is something broken repairable? What are the social relationships that take place around repair? And how much tolerance for failure do our societies have?