Biotechnology Of Bioactive Compounds

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits “bioactives’’ from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. Outlines technological advances in bioactives extraction Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sources is essential to overcoming the rising number of new diseases. In this regard, natural bioactive compounds hold tremendous potential for new drug discovery. Therefore, this field of research has become a vital area for researchers interested in understanding the chemistry, biosynthetic mechanisms, and pharmacological activities of these bioactive metabolites. This book describes the basics of bioactive plant compounds, their chemical properties, and their pharmacological biotechnological properties with regard to various human diseases and applications in the drug, cosmetics and herbal industries. It offers a valuable asset for all students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Natural bioactive compounds have become an integral part of plant-microbe interactions geared toward adaptation to environmental changes. They regulate symbiosis, induce seed germination, and manifest allelopathic effects, i.e., they inhibit the growth of competing plant species in their vicinity. In addition, the use of natural bioactive compounds and their products is considered to be suitable and safe in e.g. alternative medicine. Thus, there is an unprecedented need to meet the increasing demand for plant secondary metabolites in the flavor and fragrance, food, and pharmaceutical industries. However, it is difficult to obtain a constant quantity of compounds from the cultivated plants, as their yield fluctuates due to several factors including genotypic variations, the geography, edaphic conditions, harvesting and processing methods. Yet familiarity with these substances and the exploration of various approaches could open new avenues in their production. This book describes the basis of bioactive plant compounds, their mechanisms and molecular actions with regard to various human diseases, and their applications in the drug, cosmetic and herbal industries. Accordingly, it offers a valuable resource for students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Bioactive Compounds - Biosynthesis, Characterization, and Applications is an authoritative compilation of chapters on bioactive compounds with proven activities. It provides valuable information about biosynthesized active compounds that can be used for the further development of products in various industries. Chapters cover such topics as biosynthesis, characterization, separation, and purification, and applications of bioactive molecules. It describes and discusses bioresources of animal, vegetal, and microbial origin as potential sources of flavonoids, polysaccharides, sterols, polyphenols, amino acids, and others. This book provides insight into future developments in the field and, as such, is an essential resource for academicians, industrial researchers, and practitioners in biomolecules with biological activity. Key features: • Describes several classes of bioactive compounds and their associated activities • Highlights potential contributions of bioactive compounds as alternatives in the prevention and/or treatment of diseases • Contains information relevant to the development and use of new products

This book focuses on various types of bioactive compounds, including secondary metabolites, oligosaccharides, polysaccharides, flavonoids, peptides/proteins, carotenoid pigments, quinones, terpenes, and polyunsaturated fatty acids, and presents an overview of their nutraceutical activities. It covers the current status and future potential of food compounds, as well as extraction technologies for bioactives derived from plant, fungi and marine-derived bioactive agents. Finally, health-promoting effects of plant, fungi and marine-derived bioactive agents are discussed. Chapters come from top researchers in this area from around the globe. The volume caters to the needs of undergraduate and post-graduate students in the area of food biotechnology, food bioprocessing, biotechnology, food engineering, etc., and also contains information pertinent to researchers.

This book delves into microbial production and its implications for various industries and presents the latest advancements in the field of bioactive compound production by microorganisms. Divided into 16 chapters, the book covers a wide range of topics, starting with the emerging trends in microbial production techniques, followed by the potential of fungi and algae in producing bioactive compounds, and the applications of bioactive compounds in medicine, agriculture, and industry. Contributions from expert scientists emphasize the significance of metabolic engineering and modern analytical techniques for the extraction, purification, and structural characterization of microbial bioactive compounds. The authors also present alternative technologies and methodologies for the recovery and extraction of these compounds from microbial sources and highlight the health-promoting benefits of natural plant-derived bioactive compounds. Particular attention is given to nanocarriers and their potential for managing the delivery of bioactive compounds in therapeutic applications. The importance of actinomycetes and their bioactive potential in the agricultural sector is also discussed. In this book, readers will also find out about the importance of microbial community dynamics in Antarctica, their ecological potential, and their industrial application. The last chapter of the book offers an industrial perspective of microbial pigments and their applications. This book is a valuable resource for researchers, academics, and industry professionals seeking to understand and harness the potential of microbial bioactive compounds for sustainable development, industrial applications, and improved human well-being.

Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)

This text comprehensively covers the analysis, enzymology, physiology and genetics of valuable natural products used in the food industry that are attractive targets for biotechnological production. The focus is on the recent advances made to achieve this goal. This unique work is the first book to focus on biotechnological production of important natural products in food additives, fragrances and flavorings, and other bioactive compounds in food. The chapters offer a deep insight into modern research and the development of low molecular weight natural products. Biotechnology of Natural Products covers products in the Phenolic, Terpenoid, and Alkaloid categories, providing a full overview of the biotechnology of food additives and other low molecular weight natural products. Gene clustering and the evolution of pathways are covered, as well as future perspectives on the topic. Due to limited oil resources and increasing consumer demand for naturalness, bioprocesses are increasingly needed to meet these requirements. Novel sophisticated technologies have facilitated the elucidation of new chemical molecules, their biosynthetic pathways and biological functions. This book provides researchers with a full overview of the technologies and processes involved in the biotechnology of natural products.