Bioactive Nutrients As Dietary Supplements And Therapeutic Agents

Nutraceutical, during recent decades, has emerged as a new term in the scientific literature. Synonymously used to the term nutraceuticals in literature are dietary supplements, bioactive nutrients, functional foods, etc. This book considers how nutraceutical substances are regulated in different countries; the physiological role of dietary fibers in relation to their claimed health benefits within the scope of functional foods, dietary supplements, and nutraceuticals; prebiotics, probiotics, and synbiotics as nutraceuticals; and the nature of a large number of phytochemicals as nutraceuticals. The book also touts fruits and vegetables as Nature’s multinutraceutical capsules, as evidenced from their beneficial health effects emerging from epidemiological studies on such diseases as diabetes, hypertension, cardiovascular, cancer, osteoporosis, rheumatism, diverticulitis, etc. In light of this, international launching of campaigns on health benefits as “go for 2-5” daily servings of fruits and vegetables is also considered.

Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons: to enhance "well-being", as traditional medicines, for health promotion or disease risk reduction, and as alternatives or complements to conventional drug therapies. On a global basis, the dietary supplement industry has enjoyed rapid growth, becoming a multi-billion dollar enterprise over the last 10 years. This growth has been associated with significant changes in both the types of products available and the reasons for using these products. In many cases, these changes have occurred without the benefit of a sound scientific basis for evaluating the safety and efficacy of these products under the new conditions of use and frequently the same limited scientific evidence is used, even though current product composition, user populations, purported beneficial effects, and conditions of use may differ significantly from the available evidence or historical usage. This book presents systematic examinations of the scientific data that are available and/or needed to substantiate and evaluate the safety and efficacy of dietary supplements. A series of case studies that are illustrative of the types of scientific challenges that have been encountered in substantiating safety and efficacy for various product types are employed to point out some of the successes but also frustrations that have occurred in recent years. Discussions among presenters and participants identify the lessons learned from these experiences and formulate ideas for improved approaches to identifying research needs and for enhancing the quality and relevance of the scientific evidence available for policy decisions. Dietary Supplements and Health constitutes a useful resource for nutritionists, biochemists, public health researchers and anyone interested in herbal, alternative medicines.

In the last three decades, revolutionary achievements have taken place in nutraceutical and functional food research including the introduction of a number of cutting-edge dietary supplements supported by human clinical trials and strong patents. Novel manufacturing technologies including unique extraction processes, bioavailability improvements th

The book, Clinical Studies in Nutraceuticals and Dietary Supplements, presents extensive information on all the vital aspects and evidence-based studies on nutraceuticals and dietary supplements. The most fascinating part of this book is that the chapters explore the key concept accompanying an emphasis on recent research and developments on nutraceuticals and dietary supplements to tackle various diseases including maternal and fetal health, cancer, cardiovascular, renal disorders, hepatic disorders, hormonal disorders, and neurological dysfunction. The introspection carries updated literature reviews with relevant vital topics, quality illustrations, and well-organized tables for a better understanding of each segment. The current market scenario of these nutraceuticals and dietary supplements is the emphasis on their importance for a healthy and disease-controlled environment. This book will be useful to research scholars and scientists, as well as individuals working in the nutraceutical, dietary supplement, and functional food industries. This is an initiative to unveil the immense wealth that these nutraceuticals and dietary supplements hold and a realization of the fact that more evidence-based studies are required for its use to curb maladies and foster a healthy lifestyle.

The term nutraceuticals is applied to the products isolated from the herbal sources, nutrients or dietary supplements, processed foods, (cereals, soup and beverages) and specific diets, that may also used as medicine other than nutrition. It usually refers to the foods derived products which may sell in medicinal form, possessing physiological benefits to the host while promoting health and wellness and provide protection against chronic disorders. They may also increase the life expectancy, delay the aging and/or support the structure and function of the body organs. Demand for nutraceuticals with potential to prevent and treat chronic disorders has been interestingly increasing over the past few years. Based on food sources, nutraceuticals are classified into dietary fibers, probiotics, prebiotics, polyunsaturated fatty acids (PUFAs), vitamins, polyphenols and spices. A dietary supplement is generally considered as product containing vitamins, minerals, amino acids, and medicinal plants that are indented to be used to supplement the diet or a concentrate, metabolite, constituent, extract, or combinations of these ingredients. Broadly, nutraceuticals are any of these ingredients or supplements using for health purposes other than nutrition. This book on the fundamentals of Nutraceuticals is organized in two parts i.e., the introductory aspects of macro- and micro-nutrients, gut microbiota regulation, nutraceuticals and drug interactions, while the second part is focusing on the biological benefits of nutraceuticals in different disease states. Besides, this book is also addressing the safety aspects of nutraceuticals and phytotherapeutic support in pregnancy. Including contributions from the experts in the field, target audience (pharmacists, nutritionists, other healthcare providers, and researchers in food and nutrition sector) will be benefited with the updated literature on nutraceuticals and dietary supplements.

Addressing the increasing popularity of nutraceuticals, dietary supplements, and functional foods, this comprehensive and timely book presents an abundance of information on herbal products and their applications. The chapter authors—highly skilled, experienced, and renowned scientists and researchers from around the globe—offer up-to-date knowledge on the uses of herbal products in health management, in cancer treatment, in mental health therapy, and more. Nutraceuticals and Dietary Supplements: Advances and Applications begins with an introduction, the nomenclature, and characteristics of nutraceuticals and goes on to discuss in-depth applications for specific health issues, including cancer, diabetes, Alzheimer’s disease, alcoholism, and more. It also looks at the pros and cons as well as the analytical techniques used for the production of nutraceuticals. Chapters cover market size, regulatory perspectives, manufacturing, and in silico drug design. The book incorporates a wide diversity of case studies, research, and theories pertaining to natural products employed by developers and content experts in the field.

Consumer interest in diet and nutritional supplements is increasing dramatically. This book is designed to meet the needs of those professionals who are called upon to advise patients and the general public. It provides a valuable text for those who are researchers or decision-makers in the food and pharmaceutical industries. The text presents a thorough account of this topical subject and enables the reader to appreciate the functions of nutrients in health and common disease states, to understand the current debates over the roles of nutrients and supplements in the diet, and to answer those questions frequently asked by patients and consumers.

Functional foods and nutraceuticals are food products that naturally offer or have been modified to offer additional health benefits beyond basic nutrition. As such products have surged in popularity in recent years, it is crucial that researchers and manufacturers understand the concepts underpinning functional foods and the opportunity they represent to improve human health, reduce healthcare costs, and support economic development worldwide. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations presents a guide to functional foods from experienced professionals in key institutions around the world. The text provides background information on the health benefits, bioavailability, and safety measurements of functional foods and nutraceuticals. Subsequent chapters detail the bioactive components in functional foods responsible for these health benefits, as well as the different formulations of these products and recent innovations spurred by consumer demands. Authors emphasize product development for increased marketability, taking into account safety issues associated with functional food adulteration and solutions to be found in GMP adherence. Various food preservation methods aimed at enhancing the quality and shelf life of functional food are also highlighted. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations is the first of its kind, designed to be useful to students, teachers, nutritionists, food scientists, food technologists and public health regulators alike.

Dietary supplements are estimated to be used regularly by almost 60% of the American population, and over 300 million people worldwide. An important and ever-growing portion of this market is in botanical supplements that are derived from natural plants. Natural, however, does not necessarily mean safe, and although plants can provide health-essent

Recently, there has been a fundamental shift in the global health and wellness industry from disease treatment to preventing chronic diseases. The use of nutraceuticals and functional foods in prevention efforts could lead to a decreased dependency on drugs. The pharmaceutical industry recognizes this shift; however, serious concerns have arisen regarding the claimed efficacy, quality, and safety of products used as medical foods. This book examines the consumer and industry mindshift, including the scientific evidence of these foods as effective adjuncts to pharmacotherapy during all stages of treatment of various diseases, thus indicating that pharmaceuticals and nutraceuticals can and should coexist. It details quality, safety, and efficacy of foods, drugs, and nutrients; marketing and product positioning; regulatory perspectives; biomarkers and metabolites; probiotics; food/drug interactions; and future industry trends. In addition, food bioactives represent diet-based molecules that perform physiological roles related to disease prevention and treatment. As such, a considerable overlap exists between food bioactives and drugs—this book presents the case for comparing and contrasting foods versus drugs in several models of health and disease.