Bioactive Materials In Dentistry

Bioactive materials, or biomaterials, have the ability to interact biologically with the tissue to which it is inserted, and to stimulate the deposition of mineralized tissue. The calcium phosphate-based ceramics were the first known materials in dentistry to have bioactivity, and currently, these materials are the most used for biomedical purposes, with different morphological characteristics. In dentistry, these materials have achieved immense importance by stimulating the deposition of osseous tissue in injured bone, and by having the ability to remineralize hard tooth tissues (enamel and dentin). Furthermore, repair materials based on aggregated trioxides mineral or on calcium hydroxide are classic biomaterials and widely used in dentistry, mainly in contact with the pulp tissue or periodontal ligament, for repair processes. However, various formulations of these materials appear all the time, in search of the ideal material. In general, bioactive materials have been shown to promote the release of calcium, sodium, silicon and phosphate ions, which are metabolized by the body, having effects such as angiogenesis and antimicrobial action, which can be improved depending on the composition of the material. Pulp tissue is a highly specialized dental tissue and is the subject of intense studies about the response to biomaterials. It is also understood that some systemic alterations in individuals have an influence on the action of bioactive materials during tissue repair processes. Thus, this book will address the use of different bioactive materials in dentistry, considering the performance of these biomaterials in the hard tissues of the tooth, and the response of the dental pulp, as well as the influence of the composition of these materials and of the individual's systemic alterations in bioactivity and in antimicrobial activity. The several in vivo and in vitro tests to evaluate the bioactivity of a biomaterial will also be addressed.

Restorative biomaterials in dentistry are designed to restore the shape and function of teeth. Their applicability is related to restorative procedures such as dental restorations, dentures, dental implants, and endodontic materials. Designing Bioactive Polymeric Materials for Restorative Dentistry reviews the current state of the art for restorative biomaterials and discusses the near-future trends in this field. The book examines the biomaterials utilized in restorative dental applications (bonding, composites, cements, and ceramics) and assesses the design for these materials and the role of nanotechnology. All of the contributors are active clinical dentists and researchers in this field. FEATURES Overviews the major ongoing research efforts on developing bioactive bonding systems and composites in dental biomaterials Focuses on emerging trends in restorative dental biomaterials Incorporates evidence-based data on new restorative dental materials throughout the book Features extensive references at the end of each chapter to enhance further study Mary Anne S. Melo, DDS, MSc, PhD FADM, is an Associate Professor and Division Director of Operative Dentistry at the School of Dentistry, University of Maryland, Baltimore, Maryland.

Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry. Provides a comprehensive review of the materials science, engineering principles and recent advances in dental biomaterials Reviews the fundamentals of dental biomaterials and examines advanced materials’ applications for tissues regeneration and clinical dentistry Written by an international collaborative team of materials scientists, biomedical engineers, oral biologists and dental clinicians in order to provide a balanced perspective on the field

Restorative biomaterials in dentistry are designed to restore the shape and function of teeth. Their applicability is related to restorative procedures such as dental restorations, dentures, dental implants, and endodontic materials. Designing Bioactive Polymeric Materials for Restorative Dentistry reviews the current state of the art for restorative biomaterials and discusses the near-future trends in this field. The book examines the biomaterials utilized in restorative dental applications (bonding, composites, cements, and ceramics) and assesses the design for these materials and the role of nanotechnology. All of the contributors are active clinical dentists and researchers in this field. FEATURES Overviews the major ongoing research efforts on developing bioactive bonding systems and composites in dental biomaterials Focuses on emerging trends in restorative dental biomaterials Incorporates evidence-based data on new restorative dental materials throughout the book Features extensive references at the end of each chapter to enhance further study Mary Anne S. Melo, DDS, MSc, PhD FADM, is an Associate Professor and Division Director of Operative Dentistry at the School of Dentistry, University of Maryland, Baltimore, Maryland.

Dental Biomaterials: Imaging, Testing and Modelling reviews the materials used in this important area, their performance and how such performance can be measured and optimised. Chapters review optical and electron microscopy imaging techniques for dental biomaterial interfaces. Specific materials such as dental cements, fibre-reinforced composites, metals and alloys are discussed. There is an analysis of stresses, fracture, wear and ageing in dental biomaterials as well as an evaluation of the performance of dental adhesives and resin-dentin bonds. Chapters also review ways of assessing the performance of dental handpieces, crowns, implants and prosthesies. The book also reviews the use of computer models in such areas as bond strength and shape optimisation of dental restorations. With its distinguished editors and team of experienced contributors DDental Biomaterials: Imaging, Testing and Modelling researchers, materials scientists, engineers and dental practitioners with an essential guide to the use and performance of dental biomaterials. An essential guide to the use and performance of dental biomaterials Reviews optical and electron microscopy imaging techniques for dental biomaterial interfaces Analyses stresses, fracture, wear and ageing in dental biomaterials and evaluates the performance of dental adhesives and resin-dentin bonds

This book is a printed edition of the Special Issue Bioactive and Therapeutic Dental Materials that was published in Materials

This book provides an up-to-date perspective on oral biofilms and dental materials, equipping readers with a sound understanding of their mutual interactions. Experts from across the world comprehensively describe the main strategies that can be followed when designing modern bioactive and biomimetic dental materials, bearing in mind the goal of reducing the occurrence of pathological conditions such as secondary caries and peri-implantitis. The background to the book is the rapid expansion in the use of nanotechnologies and modern techniques to achieve levels of performance of dental materials that were unthinkable even a few years ago. Whereas conventionally dental materials have been regarded as inert, an important paradigm shift is underway: now, these materials are being conceived as bioactive and biomimetic. Modern dental materials can produce a response by interacting positively both with the host and with the biofilm permanently colonizing hard and soft tissues of the oral cavity. These materials increasingly mimic the behavior of the tissues that they are replacing. In documenting the latest knowledge in the field, this book will be of value for both scientists in the fields of nanotechnology, biofilms and dental materials and interested clinicians.

Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. Connects materials science with restorative dentistry Focuses on the unique field of intraoral tissues Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues

Bioactive materials, or biomaterials, have the ability to interact biologically with the tissue to which it is inserted, and to stimulate the deposition of mineralized tissue. The calcium phosphate-based ceramics were the first known materials in dentistry to have bioactivity, and currently, these materials are the most used for biomedical purposes, with different morphological characteristics. In dentistry, these materials have achieved immense importance by stimulating the deposition of osseous tissue in injured bone, and by having the ability to remineralize hard tooth tissues (enamel and dentin). Furthermore, repair materials based on aggregated trioxides mineral or on calcium hydroxide are classic biomaterials and widely used in dentistry, mainly in contact with the pulp tissue or periodontal ligament, for repair processes. However, various formulations of these materials appear all the time, in search of the ideal material. In general, bioactive materials have been shown to promote the release of calcium, sodium, silicon and phosphate ions, which are metabolized by the body, having effects such as angiogenesis and antimicrobial action, which can be improved depending on the composition of the material. Pulp tissue is a highly specialized dental tissue and is the subject of intense studies about the response to biomaterials. It is also understood that some systemic alterations in individuals have an influence on the action of bioactive materials during tissue repair processes. Thus, this book will address the use of different bioactive materials in dentistry, considering the performance of these biomaterials in the hard tissues of the tooth, and the response of the dental pulp, as well as the influence of the composition of these materials and of the individual's systemic alterations in bioactivity and in antimicrobial activity. The several in vivo and in vitro tests to evaluate the bioactivity of a biomaterial will also be addressed.