Basic And Clinical Neurocardiology

The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodeling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.

Novel concepts about how neurons, from the level of the heart to the sensorium, exert dynamic control over cardiac electrical & mechanical events, are presented in this volume. A focus is on how various components of neural control of the heart remodel during the evolution of cardiac pathologies.

This valuable reference provides a wide range of practical, clinical information for physicians who care for patients with neurological and cardiac problems. Clinical Neurocardiology considers neurological complications arising from cardiac surgery and other cardiac interventions describes neurological findings in heart disease patients, including brain embolism, encephalopathies, and the effects of commonly prescribed drugs discusses the prognosis, diagnosis, and treatment of cardiac arrest details the management of coexistent coronary and cerebrovascular disease reviews the effects of various toxic and metabolic disorders causing neurologic symptoms in cardiac disease patients analyzes cardiac lesions as well as cardiac and neurological findings in patients with various diseases that effect the nervous system and heart and more! With over 1700 references, tables, drawings, photographs, and micrographs, Clinical Neurocardiology benefits cardiologists; neurologists; cardiac, cardiovascular, and vascular surgeons; neurosurgeons; internists; family and primary care physicians; physiologists; neuroscientists; and graduate and medical school students in these disciplines.

Basic Clinical Neuroscience offers medical and other health professions students a clinically oriented description of human neuroanatomy and neurophysiology. This text provides the anatomic and pathophysiologic basis for understanding neurologic abnormalities through concise descriptions of functional systems with an emphasis on medically important structures and clinically important pathways. It emphasizes the localization of specific anatomic structures and pathways with neurological deficits, using anatomy enhancing 3-D illustrations. Basic Clinical Neuroscience also includes boxed clinical information throughout the text, a key term glossary section, and review questions at the end of each chapter, making this book comprehensive enough to be an excellent Board Exam preparation resource in addition to a great professional training textbook. The fully searchable text will be available online at thePoint.

New ideas about intrinsic and extrinsic cardiac intrathoracic neurons, the role of spinal cord and medullary and higher center neurons are presented. The final chapters focus on the role that autonomic neurons play in the maintenance of cardiac function in the conscious state as well as in two major clinical conditions, dysrythimias and heart failure.

This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.

In this book, we approach neurophysiology at the interface of neurology and clinical neurophysiology. The medical disciplines of the nervous system, n- rology and clinical neurophysiology, rest heavily on other sciences, notably cellular biology, neuro-anatomy, neuro-physiology, applied physics and ma- ematical biology. Existing medical textbooks on neurophysiology, neurology and clinical neurophysiology are an excellent source of the phenomenology of various principles and diseases. Here, we choose to elucidate some of the under- ing physiological, physical processes and experimental methods, intended for a broad audience – medical residents and students, as well as students in the emerging area of medical technical sciences. We feel that a good understanding of fundamentals may signi?cantly - hance insight into various aspects of clinical neurology and clinical neu- physiology. This book, therefore, is focused on a selection of clinical signs and symptoms to highlight basic principles of neurology, (neuro-)physiology and neuroanatomy. While we believe this text to be of interest to medical students or residents in neurology or clinical neurophysiology, we speci?cally aim at students - terested in contributing to new developments and innovations in neurology and clinical neurophysiology. These students are involved with patients, even though they are not trained for routine patient care.

Combining the research and study of integrative Chinese and Western Medicine, Integrative Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners. This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research. Integrates Western and Chinese medicine for a realistic scope of cardiology treatment Establishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology "Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical use Offers a reference section that lists the latest in published studies Presents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents

The heart is our most important organ and perhaps our most mysterious. Every day it pumps 9000 litres of blood and beats around 100,000 times. But the heart is more than just a pump. In all major human cultures, it is seen as the source of love, sympathy, joy, courage, strength and wisdom. Why is this so? Having witnessed the extraordinary complexity and unpredictability of human hearts in the operating theatre – each one individual in its make-up, like a fingerprint – heart surgeon Reinhard Friedl went on a search for answers. He examined closely the latest findings in neurocardiology and psychocardiology, and in The Beat of Life he shares his discoveries. In the tradition of Giulia Enders’ Gut and Norman Doidge’s The Brain That Changes Itself, he uses riveting personal stories to illustrate the complex relationship between the heart, the brain and the psyche. The Beat of Life ends with a plea: that we recognise the heart’s wisdom and adopt a more heart-centred way of living, which will lead to greater health.