Antiprogesterone Steroid Ru 486
Download and Read Antiprogesterone Steroid Ru 486 full books in PDF, ePUB, and Kindle. Read online free Antiprogesterone Steroid Ru 486 ebook anywhere anytime directly on your device. We cannot guarantee that every ebooks is available!
Author | : Etienne-Emile Baulieu |
Publisher | : Springer Science & Business Media |
Total Pages | : 347 |
Release | : 2013-03-09 |
Genre | : Nature |
ISBN | : 1468412426 |
Download The Antiprogestin Steroid RU 486 and Human Fertility Control Book in PDF, Epub and Kindle
Advances in basic biological research have proceeded rapidly in recent years. The fields of molecular genetics and immunology have experienced dramatic breakthroughs, capturing the imagination of both the scientific community and the general public. With less public notice, receptor biology has brought a cascade of new discoveries and insights. The entire science of pharmacology has been virtually rewritten in terms of receptor phenomenology. In particular, the discovery of specific receptors for steroid and protein hormones has been of seminal importance. With this new information, we have advanced our understanding of the mechanism and specifity of hormone action. We can now explain how hormones interact selectively with specific target cells and how hormones alter biochemical events within the target cells. These facts have already impacted on applied problems of clinical medicine, particularly in diagnosis and treatment of cancer and some metabolic diseases. Now, a new and important application of basic receptor biology and chemistry looms ahead. Within a few short years since the discovery of the progesterone receptor, chemists have synthesized molecules with a greater affinity for the receptor than progesterone itself and which, while occupying the receptor, fail to trigger the events which transform a target cell from the unstimulated to the stimulated state. This is the basis of the competitive inhibitory action of the anti-progestational agent, synthesized by the chemists at Roussel Uc1af, Paris, and designated RU 486.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 303 |
Release | : 1993-02-01 |
Genre | : Medical |
ISBN | : 0309049490 |
Download Clinical Applications of Mifepristone (RU486) and Other Antiprogestins Book in PDF, Epub and Kindle
Mifepristone (RU486), the first clinically available antiprogestin, has generated great interest since its discovery in the early 1980s. Today, it is recognized that mifepristone, along with other antiprogestins, has a potentially significant therapeutic role in human health and disease, with likely applicability to a variety of pregnancy-related conditions (e.g., management of labor) and to contraception, endometriosis, and cancer, among others. But because mifepristone has been studied and used most widely as a means of nonsurgical abortion, political issues have thus far limited research on the drug and prevented its introduction into the U.S. market. This book provides an unbiased evaluation of current knowledge about both the fundamental nature of antiprogestins as well as their possible use in treating numerous diseases and conditions, and it contains recommendations for future research.
Author | : Oskari Heikinheimo |
Publisher | : |
Total Pages | : 57 |
Release | : 1989 |
Genre | : |
ISBN | : 9789529005109 |
Download Antiprogesterone Steroid RU 486 Book in PDF, Epub and Kindle
Author | : Gerald I. Zatuchni |
Publisher | : HarperCollins Publishers |
Total Pages | : 498 |
Release | : 1980 |
Genre | : Health & Fitness |
ISBN | : |
Download Research Frontiers in Fertility Regulation Book in PDF, Epub and Kindle
Author | : Richard M. Hopper |
Publisher | : John Wiley & Sons |
Total Pages | : 2206 |
Release | : 2014-08-18 |
Genre | : Medical |
ISBN | : 1118470850 |
Download Bovine Reproduction Book in PDF, Epub and Kindle
Bovine Reproduction is a comprehensive, current reference providing information on all aspects of reproduction in the bull and cow. Offering fundamental knowledge on evaluating and restoring fertility in the bovine patient, the book also places information in the context of herd health where appropriate for a truly global view of bovine theriogenology. Printed in full color throughout, the book includes 83 chapters and more than 550 images, making it the most exhaustive reference available on this topic. Each section covers anatomy and physiology, breeding management, and reproductive surgery, as well as obstetrics and pregnancy wastage in the cow. Bovine Reproduction is a welcome resource for bovine practitioners, theriogenologists, and animal scientists, as well as veterinary students and residents with an interest in the cow.
Author | : Hyman J. Zimmerman |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 848 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 9780781719520 |
Download Hepatotoxicity Book in PDF, Epub and Kindle
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author | : Neil Kaplowitz |
Publisher | : CRC Press |
Total Pages | : 790 |
Release | : 2002-10-16 |
Genre | : Medical |
ISBN | : 0203909127 |
Download Drug-Induced Liver Disease Book in PDF, Epub and Kindle
Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
Author | : Nash S. Moawad |
Publisher | : Springer |
Total Pages | : 386 |
Release | : 2017-10-13 |
Genre | : Health & Fitness |
ISBN | : 3319587803 |
Download Uterine Fibroids Book in PDF, Epub and Kindle
Comprised of clinical cases presenting diverse clinical scenarios of uterine fibroids, this concise, practical casebook will provide clinicians in reproductive medicine and obstetrics/gynecology with the best real-world strategies to properly diagnose and treat the various presentations of fibroids they may encounter in daily clinical practice. Opening with chapters discussing classification and pathogenesis, effects on fertility and treatment modalities for these common tumors, each subsequent chapter is a case that provides a unique clinical presentation of a patient’s symptoms and clinical findings, diagnostic work-up and the thought process involved in navigating the treatment options as well as the supporting evidence. Cases included illustrate different types and locations of fibroids in addition to various management strategies, complications and outcomes, and selected chapters also include video clips. Pragmatic and reader-friendly, Uterine Fibroids: A Clinical Casebook is written by experts in the field and is designed to facilitate and guide reproductive medicine specialists and gynecologists in the sometimes challenging decision-making process by presenting real case scenarios that span the spectrum of fibroid presentations and treatment options.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 534 |
Release | : 1996-11-04 |
Genre | : Medical |
ISBN | : 0309175658 |
Download Contraceptive Research and Development Book in PDF, Epub and Kindle
The "contraceptive revolution" of the 1960s and 1970s introduced totally new contraceptive options and launched an era of research and product development. Yet by the late 1980s, conditions had changed and improvements in contraceptive products, while very important in relation to improved oral contraceptives, IUDs, implants, and injectables, had become primarily incremental. Is it time for a second contraceptive revolution and how might it happen? Contraceptive Research and Development explores the frontiers of science where the contraceptives of the future are likely to be found and lays out criteria for deciding where to make the next R&D investments. The book comprehensively examines today's contraceptive needs, identifies "niches" in those needs that seem most readily translatable into market terms, and scrutinizes issues that shape the market: method side effects and contraceptive failure, the challenge of HIV/AIDS and other sexually transmitted diseases, and the implications of the "women's agenda." Contraceptive Research and Development analyzes the response of the pharmaceutical industry to current dynamics in regulation, liability, public opinion, and the economics of the health sector and offers an integrated set of recommendations for public- and private-sector action to meet a whole new generation of demand.
Author | : Vera Regitz-Zagrosek |
Publisher | : Springer Science & Business Media |
Total Pages | : 599 |
Release | : 2012-10-02 |
Genre | : Medical |
ISBN | : 3642307264 |
Download Sex and Gender Differences in Pharmacology Book in PDF, Epub and Kindle
This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.