An Investigation Of Some Physical Factors Affecting Drug Release From Solids
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Author | : James Albert Seitz |
Publisher | : |
Total Pages | : 372 |
Release | : 1958 |
Genre | : |
ISBN | : |
Download An Investigation of Some Physical Factors Affecting Drug Release from Solids Book in PDF, Epub and Kindle
Author | : Navnit Shah |
Publisher | : Springer |
Total Pages | : 702 |
Release | : 2014-11-21 |
Genre | : Medical |
ISBN | : 1493915983 |
Download Amorphous Solid Dispersions Book in PDF, Epub and Kindle
This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.
Author | : Gerald Patrick Polli |
Publisher | : |
Total Pages | : 128 |
Release | : 1965 |
Genre | : |
ISBN | : |
Download Investigation of Drug Release from Solids Book in PDF, Epub and Kindle
Author | : Anh Thu Pham |
Publisher | : |
Total Pages | : 186 |
Release | : 1993 |
Genre | : |
ISBN | : |
Download Investigation of Factors Affecting Drug Release from Swelling- and Dissolution-controlled Hydroxypropylmethyl Cellulose Matrices Book in PDF, Epub and Kindle
Author | : Palmer William Taylor |
Publisher | : |
Total Pages | : 228 |
Release | : 1965 |
Genre | : Drugs |
ISBN | : |
Download Investigation of Drug Release from Solids Book in PDF, Epub and Kindle
Author | : Allan Bennett Larson |
Publisher | : |
Total Pages | : 234 |
Release | : 1969 |
Genre | : Drugs |
ISBN | : |
Download An Investigation of Various Physical Factors of Compressed Drug and how These Factors May Relate to Drug Release Book in PDF, Epub and Kindle
Author | : Jennifer B. Dressman |
Publisher | : CRC Press |
Total Pages | : 432 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 1420077341 |
Download Oral Drug Absorption Book in PDF, Epub and Kindle
Oral Drug Absorption, Second Edition thoroughly examines the special equipment and methods used to test whether drugs are released adequately when administered orally. The contributors discuss methods for accurately establishing and validating in vitro/in vivo correlations for both MR and IR formulations, as well as alternative approaches for MR an
Author | : Gerald Patrick Polli |
Publisher | : |
Total Pages | : 282 |
Release | : 1960 |
Genre | : |
ISBN | : |
Download Investigation of Drug Release from Solids Book in PDF, Epub and Kindle
Author | : Annalisa Mercuri |
Publisher | : |
Total Pages | : |
Release | : 2009 |
Genre | : |
ISBN | : |
Download A Physico-chemical Investigation Into the Factors Affecting the Behaviour of Self-emulsifying Drug Delivery Systems Book in PDF, Epub and Kindle
Author | : Dennis Douroumis |
Publisher | : John Wiley & Sons |
Total Pages | : 404 |
Release | : 2012-04-24 |
Genre | : Science |
ISBN | : 1118307879 |
Download Hot-Melt Extrusion Book in PDF, Epub and Kindle
Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.