Advanced Nanomaterials For Point Of Care Diagnosis And Therapy

Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite. Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field. Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform

"Point-of-care POC diagnostic devices are predominantly used for the diagnosis and monitoring of diseases. To make these technologies scalable for manufacturing, user-friendly, inexpensive, sensitive, and rapid, combination of such devices with nanomaterials is required. This book deals with the new emerging fields such as POC technologies, advanced nanotheranostics using nanomaterials, technologies, and applications in diagnosis. Current advances for the application of nanomaterials such as carbon nanotubes, graphene, and magnetic nanoparticles in POC devices and future directions are reviewed. Presents a comprehensive account of needs and challenges of point-of-care diagnostics. Describes the fundamentals of rationale of nanomaterials as remarkable building block for biosensing. Discusses development of critical diagnosis in point of care systems. Deals with the advantages of nanomaterial-based sensing strategies. Illustrates the challenges and breakthroughs of technologies for cost-efficient biosensing platform. The book is aimed at Researchers and professionals in nanotechnology and biomedical engineering"--

Point of care (POC) diagnostic devices are predominantly used for the diagnosis and monitoring of diseases. To make these technologies scalable for manufacturing, user-friendly, inexpensive, sensitive, and rapid, a combination of such devices with nanomaterials is required. This book deals with new emerging fields such as POC technologies and advanced nanotheranostics using nanomaterials and their technologies and applications in diagnosis. In this book, current advances for the application of nanomaterials such as carbon nanotubes, graphene, and magnetic nanoparticles in POC devices and future directions are reviewed. This book: Presents a comprehensive account of needs and challenges of POC diagnostics Describes the fundamentals of rationale of nanomaterials as remarkable building blocks for biosensing Discusses development of critical diagnosis in POC systems Deals with the advantages of nanomaterial-based sensing strategies Illustrates the challenges and breakthroughs of technologies for cost-efficient biosensing platform The book is aimed at researchers and professionals in nanotechnology and biomedical engineering.

This book chronicles the role of advanced nanomaterials and surface engineering technologies in the development of point-of-care biosensors for health and environmental monitoring. All aspects of nanomaterial synthesis and characterization, functionalization methods, sensing surface engineering, signal amplification strategies, use of innovative technologies to enhance sensor efficiency and performances, and innovative applications of nanobiosensors to tackle real-life problems are discussed in this book with a focus on optical and electrochemical based sensing. It also covers the detection of infectious diseases and various disease biomarkers, smartphone-based biosensing, and portable diagnostics module developments with a discussion on the working mechanisms of these devices in various domains. The book also illustrates the recent trends in biosensing, and an overview of the challenges and probable solutions for the translation of biosensors from laboratory prototypes to commercial success. ​

Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.

The book presents the fundamentals of nanomaterials, discusses the direct applications of nanomaterials to the biomedical sector, and explores the potential therapeutic applications of nanotheranostics. This book focuses on the fundamental features of various nanomaterials that are related to the development of biomedical technologies. These fundamental qualities are broken up into three parts: prevention, diagnostics, and therapeutics. When it comes to infectious diseases, prevention is of the utmost importance. Highly advanced nanomaterials including silver, titanium, graphene-based filters, and copper nanoparticles are used to fight infectious illnesses. Once the symptoms have been recognized in the patients, through the use of effective and straightforward nanodiagnostic techniques, the diseases can be accurately localized in either a qualitative or quantitative manner. Nanodiagnostics tools currently dominate the field of biomedical diagnostics because of their high degree of accuracy, low requirement for samples and reagents, user-friendliness, portability, and capacity to perform point-of-care (POC) applications. Nanomaterials are widely used in imaging due to many factors, including: their signal generation and amplification abilities; the ongoing development of reliant new imaging techniques, such as photoacoustic imaging and Raman imaging; their targeting potential, due to the possibility of functionalizing their surface with cancer-targeting moieties; their multimodality, since some nanomaterials can generate signals for more than one imaging technique; and their affordability. Modern therapeutics explores the various nanotechnological advances to cure the site-specific cancer treatment most prominently. The book explores the fundamentals of nanomaterials and discloses their direct application to the biomedical field. Finally, the book discusses future therapeutic applications of nanotheranostics. Audience The book will be read by scientists, researchers, and post-graduate students in the biomedical-related engineering field, nanoscience and nanotechnology, materials science, and bionanotechnology.

Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.

Pulsed Laser Induced Nanostructures in Liquids for Energy and Environmental Applications covers fundamental insights on the mechanism of pulsed laser techniques by considering various experimental conditions to accelerate hypotheses that are appropriate for the production of efficient nanomaterials. In this book, readers will learn about the major advancements in the field of pulsed laser technologies during the past decades, current applications, and future impacts of pulsed laser technologies. This book provides a comprehensive overview of the development of nanostructured catalytic materials via pulsed laser techniques, their use as energy, environment-related applications and their present trend in the industry and market. It also highlights the latest advances related to the application of these nanostructured materials produced via pulsed laser in liquid techniques in various energy (supercapacitor, batteries, and hydrogen production) and environmental remediation (wastewater treatment and conversion of waste into value-added product) processes. Recent progress on several kinds of both photo and electroactive nanomaterials is reviewed, and essential aspects which govern catalytic behaviors, and the corresponding stability, are discussed. Provides basic principles of pulsed laser–matter interaction, with a focus on the resulting material responses compared to other conventional techniques and state-of-the-art applications Offers comprehensive coverage of pulsed laser induced nanomaterials and their potential energy and environmental applications Examines the properties of pulsed laser induced nanostructures that make them so adaptable

Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications Examines smart-phone based nanodevices for field-based diagnosis with accurate information Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery