A Handbook Of Applied Statistics In Pharmacology

Statistics plays an important role in pharmacology and related subjects such as toxicology and drug discovery and development. Improper statistical tool selection for analyzing the data obtained from studies may result in wrongful interpretation of the performance or safety of drugs. This book communicates statistical tools in simple language. The

Statistics plays an important role in pharmacology and related subjects such as toxicology and drug discovery and development. Improper statistical tool selection for analyzing the data obtained from studies may result in wrongful interpretation of the performance or safety of drugs. This book communicates statistical tools in simple language. The examples used are similar to those that scientists encounter regularly in their research area. The authors provide cognitive clues for selection of appropriate tools to analyze the data obtained from the studies and explain how to interpret the result of the statistical analysis.

Providing a general guide to statistical methods used in the pharmaceutical industry, and illustrating how to use S-PLUS to implement these methods, the book explains why S-PLUS is a useful software package and discusses the results and implications of each particular application. It is targeted at graduates in biostatistics, statisticians involved in the industry as research scientists, regulators, academics, and/or consultants who want to know more about how to use S-PLUS and learn about other sub-fields within the industry, as well as statisticians in other fields who want to know more about statistical applications in the pharmaceutical industry.

This book will serve as an excellent field guide to applied toxicology and pharmacology investigators. It is an easy-to-read compilation of topics in applied statistics that might be considered a FAQ or perhaps more properly, a compilation of answers to questions that should be frequently asked, but often are not.

This book should be of interest to senior undergraduate and postgraduate students of applied statistics.

This completely updated fourth edition is designed to provide safety professionals or those studying to become safety professionals with the basic methods and principles necessary to apply statistics properly. Safety professionals often encounter statistics in the literature they read and are required to present findings or make decisions based on data analyses. Statistics can be used to justify the implementation of a program, identify areas that need to be addressed, or justify the impact that various safety programs have on losses and accidents. Safety professionals also use a variety of data in their day-to-day work. Applied Statistics in Occupational Safety and Health presents the reader with practical information to make their job easier. In addition to sample problems and solutions, the authors include easy-to-read charts and tables, appendices containing statistical tables, and a glossary of terms.

This is a text in methods of applied statistics for researchers who design and conduct experiments, perform statistical inference, and write technical reports. These research activities rely on an adequate knowledge of applied statistics. The reader both builds on basic statistics skills and learns to apply it to applicable scenarios without over-emphasis on the technical aspects. Demonstrations are a very important part of this text. Mathematical expressions are exhibited only if they are defined or intuitively comprehensible. This text may be used as a self review guidebook for applied researchers or as an introductory statistical methods textbook for students not majoring in statistics.​ Discussion includes essential probability models, inference of means, proportions, correlations and regressions, methods for censored survival time data analysis, and sample size determination. The author has over twenty years of experience on applying statistical methods to study design and data analysis in collaborative medical research setting as well as on teaching. He received his PhD from University of Southern California Department of Preventive Medicine, received a post-doctoral training at Harvard Department of Biostatistics, has held faculty appointments at UCLA School of Medicine and Harvard Medical School, and currently a biostatistics faculty member at Massachusetts General Hospital and Harvard Medical School in Boston, Massachusetts, USA.

Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences A practical guide to the use of basic principles of experimental design and statistical analysis in pharmacology Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences provides clear instructions on applying statistical analysis techniques to pharmacological data. Written by an experimental pharmacologist with decades of experience teaching statistics and designing preclinical experiments, this reader-friendly volume explains the variety of statistical tests that researchers require to analyze data and draw correct conclusions. Detailed, yet accessible, chapters explain how to determine the appropriate statistical tool for a particular type of data, run the statistical test, and analyze and interpret the results. By first introducing basic principles of experimental design and statistical analysis, the author then guides readers through descriptive and inferential statistics, analysis of variance, correlation and regression analysis, general linear modelling, and more. Lastly, throughout the textbook are numerous examples from molecular, cellular, in vitro, and in vivo pharmacology which highlight the importance of rigorous statistical analysis in real-world pharmacological and biomedical research. This textbook also: Describes the rigorous statistical approach needed for publication in scientific journals Covers a wide range of statistical concepts and methods, such as standard normal distribution, data confidence intervals, and post hoc and a priori analysis Discusses practical aspects of data collection, identification, and presentation Features images of the output from common statistical packages, including GraphPad Prism, Invivo Stat, MiniTab and SPSS Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences is an invaluable reference and guide for undergraduate and graduate students, post-doctoral researchers, and lecturers in pharmacology and allied subjects in the life sciences.